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2028281-88-9

2028281-88-9 structure
2028281-88-9 structure
  • Name: m-PEG6-(CH2)8-phosphonic acid ethyl ester
  • Chemical Name: m-PEG6-C6-phosphonic acid ethyl ester
  • CAS Number: 2028281-88-9
  • Molecular Formula: C23H49O9P
  • Molecular Weight: 500.60
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-01 15:17:31
  • Modify Date: 2025-08-25 15:13:33
  • m-PEG6-C6-phosphonic acid ethyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name m-PEG6-C6-phosphonic acid ethyl ester
Synonyms MFCD30458010
Description m-PEG6-C6-phosphonic acid ethyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C23H49O9P
Molecular Weight 500.60
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