184357-46-8

184357-46-8 structure

Name: m-PEG6-Amine
Chemical Name: 2-[2-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethanamine
CAS Number: 184357-46-8
Molecular Formula: C₁₃H₂₉NO₆
Molecular Weight: 295.37200
Catalog: Signaling Pathways Antibody-drug Conjugate ADC Linker
Create Date: 2018-12-27 18:06:30
Modify Date: 2025-08-25 18:48:03
m-PEG6-Amine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

Name	2-[2-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethanamine
Synonyms	3,6,9,12,15,18-HEXAOXANONADECAN-1-AMINE 1-amino-3,6,9,12,15,18-hexaoxanonadecane methyletherhexaethyleneglycol amine

Description	m-PEG6-Amine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker
Target	Cleavable
In Vitro	ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
References	[1]. Hervé Bouchard, et al. Peptidic linkers and cryptophycin conjugates, useful in therapy, and their preparation. WO2018206635A1.

Hazard Codes	Xi

1043884-49-6

~61%

184357-46-8

Literature: Seguer, J.; Selve, C.; Allouch, M.; Infante, M. R. Journal of the American Oil Chemists' Society, 1996 , vol. 73, # 1 p. 79 - 86

23601-40-3

184357-46-8

Literature: Journal of the American Oil Chemists' Society, , vol. 73, # 1 p. 79 - 86

155887-96-0

184357-46-8

Literature: Journal of the American Oil Chemists' Society, , vol. 73, # 1 p. 79 - 86

2615-15-8

184357-46-8

Literature: Journal of the American Chemical Society, , vol. 117, # 23 p. 6249 - 6253

Precursor 3
1043884-49-6 23601-40-3 2615-15-8
DownStream 0