75427-75-7

75427-75-7 structure

75427-75-7 structure

Name: 2,5,8,11,14,17,20-Heptaoxadocosan-22-oic acid
Chemical Name: m-PEG6-O-CH2COOH
CAS Number: 75427-75-7
Molecular Formula: C₁₅H₃₀O₉
Molecular Weight: 354.39
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2020-06-01 12:45:09
Modify Date: 2024-01-12 12:39:38
m-PEG6-O-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	m-PEG6-O-CH2COOH
Synonyms	MFCD30536159

Description	m-PEG6-O-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula	C₁₅H₃₀O₉
Molecular Weight	354.39