Dapoxetine-d6

Modify Date: 2024-01-12 20:49:47

Dapoxetine-d6 Structure
Dapoxetine-d6 structure
Common Name Dapoxetine-d6
CAS Number 1132642-58-0 Molecular Weight 311.45
Density N/A Boiling Point N/A
Molecular Formula C21H17D6NO Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Dapoxetine-d6


Dapoxetine-d6 is the deuterium labeled Dapoxetine[1]. Dapoxetine (LY-210448) is an orally active and selective serotonin reuptake inhibitor (SSRI). Dapoxetine can be used for the research of premature ejaculation (PE)[2].

 Names

Name Dapoxetine-d6

 Dapoxetine-d6 Biological Activity

Description Dapoxetine-d6 is the deuterium labeled Dapoxetine[1]. Dapoxetine (LY-210448) is an orally active and selective serotonin reuptake inhibitor (SSRI). Dapoxetine can be used for the research of premature ejaculation (PE)[2].
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  

[2]. Muammer Kendirci, et al. Dapoxetine, a novel selective serotonin transport inhibitor for the treatment of premature ejaculation. Ther Clin Risk Manag. 2007 Jun;3(2):277-89.  

[3]. Rabab H Sayed, et al. Dapoxetine attenuates testosterone-induced prostatic hyperplasia in rats by the regulation of inflammatory and apoptotic proteins. Toxicol Appl Pharmacol. 2016 Nov 15;311:52-60.  

 Chemical & Physical Properties

Molecular Formula C21H17D6NO
Molecular Weight 311.45