4-Aminoacetophenone

Modify Date: 2024-01-02 22:33:02

4-Aminoacetophenone Structure
4-Aminoacetophenone structure
Common Name 4-Aminoacetophenone
CAS Number 99-92-3 Molecular Weight 135.16
Density 1.1±0.1 g/cm3 Boiling Point 294.8±13.0 °C at 760 mmHg
Molecular Formula C8H9NO Melting Point 103-107 °C(lit.)
MSDS Chinese USA Flash Point 132.1±19.8 °C
Symbol GHS07
GHS07
Signal Word Warning

 Use of 4-Aminoacetophenone


1-(4-Aminophenyl)ethanone is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

 Names

Name 4-Aminoacetophenone
Synonym More Synonyms

 4-Aminoacetophenone Biological Activity

Description 1-(4-Aminophenyl)ethanone is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
Related Catalog

 Chemical & Physical Properties

Density 1.1±0.1 g/cm3
Boiling Point 294.8±13.0 °C at 760 mmHg
Melting Point 103-107 °C(lit.)
Molecular Formula C8H9NO
Molecular Weight 135.16
Flash Point 132.1±19.8 °C
Exact Mass 135.068420
PSA 43.09000
LogP 0.41
Vapour Pressure 0.0±0.6 mmHg at 25°C
Index of Refraction 1.571

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
AM5500000
CHEMICAL NAME :
Acetophenone, p-amino-
CAS REGISTRY NUMBER :
99-92-3
BEILSTEIN REFERENCE NO. :
0471493
LAST UPDATED :
199701
DATA ITEMS CITED :
7
MOLECULAR FORMULA :
C8-H9-N-O
MOLECULAR WEIGHT :
135.18
WISWESSER LINE NOTATION :
ZR DV1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
381 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
GEPHDP General Pharmacology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.6- 1975- Volume(issue)/page/year: 14,465,1983
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
260 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 80,31,1944
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
596 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
GEPHDP General Pharmacology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.6- 1975- Volume(issue)/page/year: 14,465,1983
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
300 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: AD277-689
TYPE OF TEST :
LD - Lethal dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Mammal - dog
DOSE/DURATION :
>70 mg/kg
TOXIC EFFECTS :
Blood - methemoglobinemia-carboxyhemoglobin
REFERENCE :
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 80,31,1944
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Bird - wild bird species
DOSE/DURATION :
133 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AECTCV Archives of Environmental Contamination and Toxicology. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 070944) V.1- 1973- Volume(issue)/page/year: 12,355,1983

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H302
Precautionary Statements P301 + P312 + P330
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Faceshields;Gloves
Hazard Codes Xn:Harmful;
Risk Phrases R22
Safety Phrases S26-S36
RIDADR NONH for all modes of transport
WGK Germany 3
RTECS AM5500000
HS Code 29223900

 Synthetic Route

 Customs

HS Code 2922399090
Summary 2922399090 other amino-aldehydes, amino-ketones and amino-quinones, other than those containing more than one kind of oxygen function; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

 Articles10

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Synthesis of aryl semicarbazone of 4-aminoacetophenone and their anti-HIV activity.

Pharm. Acta Helv. 73(4) , 215-8, (1998)

The thioureido derivative of 4-aminoacetophenone aryl semicarbazone have been prepared. These derivatives have been characterised on the basis of different physicochemical evidences. The anti-HIV-1 (H...

[Determination of p-aminoacetophenone and changes in its levels in a levorin producer depending on culture conditions].

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A method for spectrophotometric determination of p-aminoacetophenone (p-AAP) in the mycelium and fermentation broth filtrates of organisms producing polyenic macrolide antibiotics is described. The le...

 Synonyms

1-(4-Aminophenyl)ethanone
MFCD00007896
p-Aminoacetylbenzene
p-Aminoacetophenone
Ethanone, 1-(4-aminophenyl)-
p-acetylaniline
4-Acetylaniline
4-Amino acetophenone
EINECS 202-801-2
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