Sulfaethoxypyridazine

Modify Date: 2024-01-03 09:45:29

Sulfaethoxypyridazine Structure
Sulfaethoxypyridazine structure
Common Name Sulfaethoxypyridazine
CAS Number 963-14-4 Molecular Weight 294.33000
Density 1.416g/cm3 Boiling Point 565.9ºC at 760mmHg
Molecular Formula C12H14N4O3S Melting Point 182-184ºC
MSDS USA Flash Point 296ºC

 Use of Sulfaethoxypyridazine


Sulfaethoxypyridazine is a sulfonamide antibacterial agent. Sulfaethoxypyridazine is a sulfonamide that is used in veterinary medicine as feedstuffs[1].

 Names

Name 4-amino-N-(6-ethoxypyridazin-3-yl)benzenesulfonamide
Synonym More Synonyms

 Sulfaethoxypyridazine Biological Activity

Description Sulfaethoxypyridazine is a sulfonamide antibacterial agent. Sulfaethoxypyridazine is a sulfonamide that is used in veterinary medicine as feedstuffs[1].
Related Catalog
Target

Antibacterial[1]

In Vivo Feeding of Sulfaethoxypyridazine, a long-acting sulfonamide, to rats at dietary levels of 800, 1600, and 3200 ppm resulted in the development of characteristic lens opacities by 23 weeks. Daily oral administration of 30, 67, and 150 mg/kg to dogs resulted in the development of similar cataracts by 14 weeks[1].
References

[1]. Ribelin WE, et al. Development of cataracts in dogs and rats from prolonged feeding of sulfaethoxypyridazine. Toxicol Appl Pharmacol. 1967 May;10(3):557-64.

 Chemical & Physical Properties

Density 1.416g/cm3
Boiling Point 565.9ºC at 760mmHg
Melting Point 182-184ºC
Molecular Formula C12H14N4O3S
Molecular Weight 294.33000
Flash Point 296ºC
Exact Mass 294.07900
PSA 115.58000
LogP 2.99330
Index of Refraction 1.632

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
WO9410000
CHEMICAL NAME :
Sulfanilamide, N(sup 1)-(6-ethoxy-3-pyridazinyl)-
CAS REGISTRY NUMBER :
963-14-4
BEILSTEIN REFERENCE NO. :
0286161
LAST UPDATED :
199612
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C12-H14-N4-O3-S
MOLECULAR WEIGHT :
294.36

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
16240 mg/kg/29W-I
TOXIC EFFECTS :
Sense Organs and Special Senses (Eye) - effect, not otherwise specified Endocrine - changes in pituitary weight Endocrine - changes in thyroid weight
REFERENCE :
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 10,557,1967
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Mammal - dog
DOSE/DURATION :
30450 mg/kg/29W-I
TOXIC EFFECTS :
Sense Organs and Special Senses (Eye) - effect, not otherwise specified Endocrine - changes in thyroid weight Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol)
REFERENCE :
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 10,557,1967

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADR NONH for all modes of transport
RTECS WO9410000
HS Code 2935009090

 Synthetic Route

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Sulfaethoxypyridazine Structure

Sulfaethoxypyri...

CAS#:963-14-4

Literature: Journal of the American Chemical Society, , vol. 80, p. 980,982

 Customs

HS Code 2935009090
Summary 2935009090 other sulphonamides VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:35.0%

 Articles1

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J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 972 , 38-47, (2014)

A liquid chromatography-tandem mass spectrometry (LC-MS/MS) screening method is described for the detection and identification of 26 veterinary drugs in fish and other aquaculture products. The analyt...

 Synonyms

Cysul
EINECS 213-514-7
3-Sulfanilylamino-6-aethoxy-pyridazin
6-Aethoxy-3-sulfanilamino-pyridazin
SULFAETHOXYPYRIDAZINE
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