Trimidox

Modify Date: 2024-01-10 14:08:39

Trimidox Structure
Trimidox structure
Common Name Trimidox
CAS Number 95933-74-7 Molecular Weight 184.15
Density 1.7±0.1 g/cm3 Boiling Point 480.7±55.0 °C at 760 mmHg
Molecular Formula C7H8N2O4 Melting Point N/A
MSDS N/A Flash Point 244.5±31.5 °C

 Use of Trimidox


Trimidox (VF-233) is a ribonucleotide reductase inhibitor with antileukemic activities. Trimidox inhibits the growth of human promyelocytic leukemia HL-60 cells with an IC50 of 35 μM[1].

 Names

Name 4-[amino-(hydroxyamino)methylidene]-2,6-dihydroxycyclohexa-2,5-dien-1-one
Synonym More Synonyms

 Trimidox Biological Activity

Description Trimidox (VF-233) is a ribonucleotide reductase inhibitor with antileukemic activities. Trimidox inhibits the growth of human promyelocytic leukemia HL-60 cells with an IC50 of 35 μM[1].
Related Catalog
References

[1]. T Szekeres, et al. Synergistic growth inhibitory and differentiating effects of trimidox and tiazofurin in human promyelocytic leukemia HL-60 cells. Blood. 1994 Dec 15;84(12):4316-21.  

 Chemical & Physical Properties

Density 1.7±0.1 g/cm3
Boiling Point 480.7±55.0 °C at 760 mmHg
Molecular Formula C7H8N2O4
Molecular Weight 184.15
Flash Point 244.5±31.5 °C
Exact Mass 184.048401
PSA 116.80000
LogP -0.12
Vapour Pressure 0.0±1.3 mmHg at 25°C
Index of Refraction 1.681

 Synonyms

2,5-Cyclohexadien-1-one, 4-[amino(hydroxyamino)methylene]-2,6-dihydroxy-
Trimidox
Benzenecarboximidamide,N,3,4,5-tetrahydroxy
N,3,4,5-TETRAHYDROXY-BENZENECARBOXIMIDAMIDE
4-[Amino(hydroxyamino)methylene]-2,6-dihydroxy-2,5-cyclohexadien-1-one
Benzenecarboximidamide, N,3,4,5-tetrahydroxy-
3,4,5-Trihydroxybenzamidoxime
N,3,4,5-Tetrahydroxybenzenecarboximidamide
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.