CFTR corrector 12

Modify Date: 2024-01-17 15:05:08

CFTR corrector 12 structure	Common Name	CFTR corrector 12
	CAS Number	958941-60-1	Molecular Weight	436.98
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₉H₂₁ClN₄O₂S₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of CFTR corrector 12

CFTR corrector 12 (compound 17C) is a bithiazole derivative, serving as CFTR corrector. CFTR corrector 12 has the ability to correct some folding defective mutants of the channel responsible for the control of chloride transport across the plasma membrane. CFTR corrector 12 recovers the α-sarcoglycan (α-SG) content in mutant cells[1].

Name	CFTR corrector 12

Description	CFTR corrector 12 (compound 17C) is a bithiazole derivative, serving as CFTR corrector. CFTR corrector 12 has the ability to correct some folding defective mutants of the channel responsible for the control of chloride transport across the plasma membrane. CFTR corrector 12 recovers the α-sarcoglycan (α-SG) content in mutant cells[1].
Related Catalog	Signaling Pathways >> Membrane Transporter/Ion Channel >> CFTR Research Areas >> Others
References	[1]. Ribaudo G, et al. Synthesis and Evaluation of Bithiazole Derivatives As Potential α-Sarcoglycan Correctors. ACS Med Chem Lett. 2023 Jul 28;14(8):1049-1053.

Molecular Formula	C₁₉H₂₁ClN₄O₂S₂
Molecular Weight	436.98

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CFTR corrector 12

Use of CFTR corrector 12

Names

CFTR corrector 12 Biological Activity

Chemical & Physical Properties