958941-60-1

958941-60-1 structure
958941-60-1 structure
  • Name: CFTR corrector 12
  • Chemical Name: CFTR corrector 12
  • CAS Number: 958941-60-1
  • Molecular Formula: C19H21ClN4O2S2
  • Molecular Weight: 436.98
  • Catalog: Signaling Pathways Membrane Transporter/Ion Channel CFTR
  • Create Date: 2023-11-11 10:47:01
  • Modify Date: 2024-01-17 15:05:08
  • CFTR corrector 12 (compound 17C) is a bithiazole derivative, serving as CFTR corrector. CFTR corrector 12 has the ability to correct some folding defective mutants of the channel responsible for the control of chloride transport across the plasma membrane. CFTR corrector 12 recovers the α-sarcoglycan (α-SG) content in mutant cells[1].

Name CFTR corrector 12
Description CFTR corrector 12 (compound 17C) is a bithiazole derivative, serving as CFTR corrector. CFTR corrector 12 has the ability to correct some folding defective mutants of the channel responsible for the control of chloride transport across the plasma membrane. CFTR corrector 12 recovers the α-sarcoglycan (α-SG) content in mutant cells[1].
Related Catalog
References

[1]. Ribaudo G, et al. Synthesis and Evaluation of Bithiazole Derivatives As Potential α-Sarcoglycan Correctors. ACS Med Chem Lett. 2023 Jul 28;14(8):1049-1053.

Molecular Formula C19H21ClN4O2S2
Molecular Weight 436.98