1,2,4,5-Tetrachlorobenzene

Modify Date: 2025-08-25 16:03:17

1,2,4,5-Tetrachlorobenzene structure	Common Name	1,2,4,5-Tetrachlorobenzene
	CAS Number	95-94-3	Molecular Weight	215.892
	Density	1.6±0.1 g/cm3	Boiling Point	246.9±35.0 °C at 760 mmHg
	Molecular Formula	C₆H₂Cl₄	Melting Point	139 °C
	MSDS	Chinese USA	Flash Point	108.2±23.3 °C
	Symbol	GHS07, GHS09	Signal Word	Warning

Name	1,2,4,5-tetrachlorobenzene
Synonym	More Synonyms

Density	1.6±0.1 g/cm3
Boiling Point	246.9±35.0 °C at 760 mmHg
Melting Point	139 °C
Molecular Formula	C₆H₂Cl₄
Molecular Weight	215.892
Flash Point	108.2±23.3 °C
Exact Mass	213.891068
LogP	4.23
Vapour Pressure	0.0±0.5 mmHg at 25°C
Index of Refraction	1.583
Stability	Stable. Combustible. Incompatible with strong oxidizing agents. Reacts explosively with alkaline methanol solutions.
Water Solubility	insoluble.

1,2,4,5-Tetrachlorobenzene MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: DB9450000

CHEMICAL NAME :: Benzene, 1,2,4,5-tetrachloro-

CAS REGISTRY NUMBER :: 95-94-3

BEILSTEIN REFERENCE NO. :: 1618315

LAST UPDATED :: 199712

DATA ITEMS CITED :: 19

MOLECULAR FORMULA :: C6-H2-Cl4

MOLECULAR WEIGHT :: 215.88

WISWESSER LINE NOTATION :: GR BG DG EG

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1500 mg/kg

TOXIC EFFECTS :: Behavioral - general anesthetic Behavioral - somnolence (general depressed activity) Behavioral - convulsions or effect on seizure threshold

REFERENCE :: HYSAAV Hygiene and Sanitation (USSR). English translation of GISAAA. (Springfield, VA) 1964-71. Discontinued. Volume(issue)/page/year: 30(1-3),8,1965

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1035 mg/kg

TOXIC EFFECTS :: Behavioral - general anesthetic Behavioral - somnolence (general depressed activity) Behavioral - convulsions or effect on seizure threshold

REFERENCE :: HYSAAV Hygiene and Sanitation (USSR). English translation of GISAAA. (Springfield, VA) 1964-71. Discontinued. Volume(issue)/page/year: 30(1-3),8,1965

TYPE OF TEST :: LD - Lethal dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: CBCCT* "Summary Tables of Biological Tests," National Research Council Chemical-Biological Coordination Center. (National Academy of Science Library, 2101 Constitution Ave., NW, Washington, DC 20418) Volume(issue)/page/year: 4,107,1952

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 1500 mg/kg

TOXIC EFFECTS :: Behavioral - convulsions or effect on seizure threshold Behavioral - changes in motor activity (specific assay) Behavioral - muscle weakness

REFERENCE :: GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 30(1),9,1965 ** OTHER MULTIPLE DOSE TOXICITY DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 5460 mg/kg/13W-C

TOXIC EFFECTS :: Liver - changes in liver weight Kidney, Ureter, Bladder - other changes in urine composition Blood - pigmented or nucleated red blood cells

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: PB91-185330

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 896 mg/kg/28D-C

TOXIC EFFECTS :: Liver - changes in liver weight Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol) Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - hepatic microsomal mixed oxidase (dealkylation, hydroxylation, etc.)

REFERENCE :: JTEHD6 Journal of Toxicology and Environmental Health. (Hemisphere Pub., 1025 Vermont Ave., NW, Washington, DC 20005) V.1- 1975/76- Volume(issue)/page/year: 11,663,1983

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 2700 mg/kg/90D-C

TOXIC EFFECTS :: Liver - changes in liver weight Kidney, Ureter, Bladder - changes in bladder weight Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol)

REFERENCE :: DCTODJ Drug and Chemical Toxicology. (Marcel Dekker, 270 Madison Ave., New York, NY 10016) V.1- 1977/78- Volume(issue)/page/year: 7,113,1984

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 4567 mg/kg/9W-I

TOXIC EFFECTS :: Endocrine - changes in adrenal weight Blood - changes in bone marrow (not otherwise specified) Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - true cholinesterase

REFERENCE :: GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 30(1),9,1965

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 12 mg/kg/35W-I

TOXIC EFFECTS :: Behavioral - alteration of classical conditioning Liver - changes in liver weight

REFERENCE :: GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 30(1),9,1965

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 2100 mg/kg/14D-C

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Lungs, Thorax, or Respiration - dyspnea Related to Chronic Data - death

REFERENCE :: NTPTR* National Toxicology Program Technical Report Series. (Research Triangle Park, NC 27709) No.206- Volume(issue)/page/year: NIH-91-3126

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 4550 mg/kg/13W-C

TOXIC EFFECTS :: Liver - changes in liver weight Blood - microcytosis with or without anemia Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - dehydrogenases

REFERENCE :: NTPTR* National Toxicology Program Technical Report Series. (Research Triangle Park, NC 27709) No.206- Volume(issue)/page/year: NIH-91-3126

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 12 mg/kg/35W-I

TOXIC EFFECTS :: Blood - pigmented or nucleated red blood cells Blood - changes in other cell count (unspecified)

REFERENCE :: GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 30(1),9,1965

Symbol	GHS07, GHS09
Signal Word	Warning
Hazard Statements	H302-H315-H319-H335-H410
Precautionary Statements	P261-P273-P305 + P351 + P338-P501
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xn:Harmful;
Risk Phrases	R22;R36/37/38
Safety Phrases	S26-S36-S45-S27-S16
RIDADR	UN 3077 9/PG 3
WGK Germany	3
RTECS	DB9450000
Packaging Group	I; II; III
Hazard Class	6.1
HS Code	29036990

Precursor 9
CAS#:118-74-1 Hexachlorobenzene CAS#:71-43-2 benzene CAS#:13074-99-2 1,4-dibromo-2,3... CAS#:58327-36-9 α-Bromo-α-(4-me...
CAS#:58327-37-0 α-Chloro-α-(4-m... CAS#:824-72-6 phenylphosphoni... CAS#:608-93-5 Benzene,1,2,3,4... CAS#:372-18-9 1,3-Difluorobenzene
CAS#:313-72-4 Octafluoronapht...
DownStream 10
CAS#:105633-26-9 3-[bis(2,3,5,6-... CAS#:105633-33-8 2,3,5,6-Tetrach... CAS#:50-82-8 2,4,5-Trichloro... CAS#:108-90-7 Chlorobenzene
CAS#:71-43-2 benzene CAS#:50-79-3 2,5-Dichloroben... CAS#:92-52-4 Biphenyl CAS#:15862-07-4 2,4,5-Trichloro...
CAS#:35065-27-1 PCB-153 CAS#:447463-65-2 1,2,4,5-Tetra-T...

HS Code	2903999090
Summary	2903999090 halogenated derivatives of aromatic hydrocarbons VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%

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MFCD00000549

Benzene, 1,2,4,5-tetrachloro-

1,2,4,5-Tetrachlorobenzene

EINECS 202-466-2

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China
Product Name: 1,2,4,5-Tetrachlorobenzene
Price: Check
Purity: 98.0%
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China
Product Name: 1,2,4,5-Tetrachlorobenzene
Price: ￥208.0/2ml
Purity: 98.0%
Delivery: 1 Day
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Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 1,2,4,5-Tetrachlorobenzene
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Delivery: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

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1,2,4,5-Tetrachlorobenzene

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