2-Chloro-4-aminotoluene

Modify Date: 2024-01-02 18:16:30

2-Chloro-4-aminotoluene Structure
2-Chloro-4-aminotoluene structure
Common Name 2-Chloro-4-aminotoluene
CAS Number 95-74-9 Molecular Weight 141.598
Density 1.2±0.1 g/cm3 Boiling Point 243.1±20.0 °C at 760 mmHg
Molecular Formula C7H8ClN Melting Point 25 °C
MSDS Chinese USA Flash Point 100.8±21.8 °C
Symbol GHS06 GHS09
GHS06, GHS09
Signal Word Danger

 Names

Name 3-chloro-p-toluidine
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 243.1±20.0 °C at 760 mmHg
Melting Point 25 °C
Molecular Formula C7H8ClN
Molecular Weight 141.598
Flash Point 100.8±21.8 °C
Exact Mass 141.034531
PSA 26.02000
LogP 2.27
Vapour Pressure 0.0±0.5 mmHg at 25°C
Index of Refraction 1.585
Storage condition 2-8°C
Stability Stable. Combustible. Incompatible with strong oxidizing agents, acid chlorides, acids, acid anhydrides, chloroformates, reducing agents.
Water Solubility 1 g/L (20 ºC)

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
XU5111000
CHEMICAL NAME :
p-Toluidine, 3-chloro-
CAS REGISTRY NUMBER :
95-74-9
BEILSTEIN REFERENCE NO. :
0636511
LAST UPDATED :
199710
DATA ITEMS CITED :
15
MOLECULAR FORMULA :
C7-H8-Cl-N
MOLECULAR WEIGHT :
141.61
WISWESSER LINE NOTATION :
ZR CG D1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1500 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
325 mg/kg
TOXIC EFFECTS :
Behavioral - muscle weakness Lungs, Thorax, or Respiration - dyspnea Lungs, Thorax, or Respiration - cyanosis
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
48 mg/kg
TOXIC EFFECTS :
Behavioral - muscle weakness Lungs, Thorax, or Respiration - dyspnea Lungs, Thorax, or Respiration - cyanosis
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
316 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Bird - pigeon
DOSE/DURATION :
13 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Bird - quail
DOSE/DURATION :
1 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Bird - wild bird species
DOSE/DURATION :
2400 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
Unscheduled DNA synthesis
TYPE OF TEST :
Mutation test systems - not otherwise specified

MUTATION DATA

TEST SYSTEM :
Rodent - mouse
DOSE/DURATION :
200 mg/kg
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 46,305,1977

 Safety Information

Symbol GHS06 GHS09
GHS06, GHS09
Signal Word Danger
Hazard Statements H301 + H311-H315-H317-H319-H410
Precautionary Statements P273-P280-P301 + P310-P305 + P351 + P338-P312-P501
Personal Protective Equipment Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges
Hazard Codes Xn:Harmful
Risk Phrases R22;R36/37/38;R50/53
Safety Phrases S36/37/39-S45-S61-S60-S36/37-S26
RIDADR UN 2239 6.1/PG 3
WGK Germany 2
RTECS XU5111000
Packaging Group III
Hazard Class 6.1

 Synthetic Route

 Articles9

More Articles
[Method of determining p-nitrotoluene, 2-chloro-4-nitrotoluene and 3-chloro-4-methylaniline in the air].

Gig. Tr. Prof. Zabol. (1) , 43-4, (1980)

Pathological features of 3-chloro-4-methyl benzamine HCl toxicity in rooks (Corvus frugilegus L.) and pheasants (Phasianus colchicus L.).

Gegenbaurs Morphol. Jahrb. 128(5) , 753-61, (1982)

Gross and microscopic changes in response to single po. doses of avicide 3-chloro-4-methyl benzamine HCl were studied in rooks (Corvus frugilegus L.) and pheasants (Phasianus colchicus L.). The observ...

Stabilization of the avicide 3-chloro-p-toluidine as the beta-cyclodextrin adduct.

J. Agric. Food Chem. 47(7) , 2904-7, (1999)

Stabilization of the avicide 3-chloro-p-toluidine (CPTH) on rice baits by pseudo latex polymeric coating and beta-cyclodextin inclusion was investigated. When CPTH-treated rice baits were exposed to s...

 Synonyms

4-Amino-2-chlorotoluene
4-methyl-5-chloroaniline
3-chloro-4-methylphenylamine
2B oil
CPT
EINECS 202-446-3
3-CHLORO-P-TOLUIDINE
4-Methyl-3-chloroaniline
2-Chloro-4-Aminotoluene Or O-Chloro-P-Aminotoluene
DKC 1347
MFCD00007773
2-chloro-4-amino-toluene
3-CHLOR-4-METHYLANILIN
2-Chloro-4-aminotoluene
1-Amino-3-chloro-4-methylbenzene
3-Chloro-4-methylanilin
2-CHLORO-4-TOLUIDINE
3-CHLORO-4-METHYLANILINE D
3-cpt
DRC 1339
Benzenamine, 3-chloro-4-methyl-
3-Chloro-4-methylaniline
O-CHLORO-P-TOLUIDINE
drc1347
OCPT
Starlicide
cpt[qr]
3-CHLORO-P-TOLUIDINE (NH2=1)
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