Chlortoluron

Modify Date: 2024-01-02 22:46:26

Chlortoluron Structure
Chlortoluron structure
Common Name Chlortoluron
CAS Number 15545-48-9 Molecular Weight 212.676
Density 1.2±0.1 g/cm3 Boiling Point 345.9±52.0 °C at 760 mmHg
Molecular Formula C10H13ClN2O Melting Point 147-148ºC
MSDS Chinese USA Flash Point 163.0±30.7 °C
Symbol GHS08 GHS09
GHS08, GHS09
Signal Word Warning

 Use of Chlortoluron


Chlorotoluron (Chlortoluron) is a substituted phenylurea herbicide, is widely used for selective weed control in cereals crops and is an environmental pollutant[1].

 Names

Name chlorotoluron
Synonym More Synonyms

 Chlortoluron Biological Activity

Description Chlorotoluron (Chlortoluron) is a substituted phenylurea herbicide, is widely used for selective weed control in cereals crops and is an environmental pollutant[1].
Related Catalog
References

[1]. Z Mehmood, et al. Metabolism of the Herbicide Chlortoluron by Human Cytochrome P450 3A4. Chemosphere. 1995 Dec;31(11-12):4515-29.

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 345.9±52.0 °C at 760 mmHg
Melting Point 147-148ºC
Molecular Formula C10H13ClN2O
Molecular Weight 212.676
Flash Point 163.0±30.7 °C
Exact Mass 212.071640
PSA 32.34000
LogP 2.62
Vapour Pressure 0.0±0.8 mmHg at 25°C
Index of Refraction 1.541

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
YS7230000
CHEMICAL NAME :
Urea, 3-(3-chloro-p-tolyl)-1,1-dimethyl-
CAS REGISTRY NUMBER :
15545-48-9
BEILSTEIN REFERENCE NO. :
2647688
LAST UPDATED :
199701
DATA ITEMS CITED :
9
MOLECULAR FORMULA :
C10-H13-Cl-N2-O
MOLECULAR WEIGHT :
212.70
WISWESSER LINE NOTATION :
GR B1 EMVN1&1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
5800 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1300 mg/m3
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>2 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Mammal - dog
DOSE/DURATION :
21 gm/kg/90D-C
TOXIC EFFECTS :
Behavioral - food intake (animal) Nutritional and Gross Metabolic - weight loss or decreased weight gain Related to Chronic Data - death
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
2 gm/kg
SEX/DURATION :
female 4 day(s) after conception
TOXIC EFFECTS :
Reproductive - Fertility - pre-implantation mortality (e.g. reduction in number of implants per female; total number of implants per corpora lutea) Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants)
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
10 mg/kg
SEX/DURATION :
male 50 day(s) pre-mating
TOXIC EFFECTS :
Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus)

MUTATION DATA

TEST SYSTEM :
Rodent - mouse
DOSE/DURATION :
200 mg/kg
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 58,353,1978

 Safety Information

Symbol GHS08 GHS09
GHS08, GHS09
Signal Word Warning
Hazard Statements H351-H361d-H410
Precautionary Statements P273-P281-P501
Hazard Codes Xn:Harmful;N:Dangerousfortheenvironment;
Risk Phrases R40;R50/53;R63
Safety Phrases S26-S36/37-S46-S60-S61-S16
RIDADR UN 3077
RTECS YS7230000
HS Code 2924299035

 Customs

HS Code 2924299035
Summary 2924299035 2-chlorobenzaldehyde。supervision conditions:s(import or export registration certificate for pesticides)。VAT:17.0%。tax rebate rate:9.0%。MFN tarrif:6.5%。general tariff:30.0%

 Articles26

More Articles
Assessing the potential for algae and macrophytes to degrade crop protection products in aquatic ecosystems.

Environ. Toxicol. Chem. 30(3) , 622-31, (2011)

Rates of pesticide degradation in aquatic ecosystems often differ between those observed within laboratory studies and field trials. Under field conditions, a number of additional processes may well h...

Polymer monolith microextraction using poly(butyl methacrylate-co-1,6-hexanediol ethoxylate diacrylate) monolithic sorbent for determination of phenylurea herbicides in water samples.

Talanta 147 , 199-206, (2015)

In this study, recently developed 1,6-hexanediol ethoxylate diacrylate (HEDA)-based polymeric monoliths were utilized as sorbents for efficient extraction of phenylurea herbicides (PUHs) from water sa...

Analysis of trace levels of pesticides in rainwater by SPME and GC-tandem mass spectrometry after derivatisation with PFBBr.

Anal. Bioanal. Chem 387(1) , 359-68, (2007)

Solid-phase microextraction (SPME) was used for the analysis of some pesticides (bromoxynil, chlorotoluron, diuron, isoproturon, 2,4-MCPA, MCPP and 2,4-D) in rainwater after derivatisation with PFBBr ...

 Synonyms

Chlorotoluron
Methanol, 1-[(3-chloro-4-methylphenyl)imino]-1-(dimethylamino)-, (E)-
Urea, N'-(3-chloro-4-methylphenyl)-N,N-dimethyl-
N’-(3-chloro-4-methylphenyl)-N,N-dimethylurea
3-(3-Chloro-4-methylphenyl)-1,1-dimethylurea
MFCD00018275
Chlortoluron
3-(3-chloro-p-tolyl)-1,1-dimethylurea
EINECS 239-592-2
3-(3-Chloro-4-methyl)-1,1-dimethylurea
N'-(3-Chloro-4-methylphenyl)-N,N-dimethylcarbamimidic acid
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