BI-1935
Modify Date: 2024-01-09 12:57:07
BI-1935 structure
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Common Name | BI-1935 | ||
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| CAS Number | 940954-41-6 | Molecular Weight | 498.466 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C24H21F3N6O3 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of BI-1935BI-1935 is a potent, selective small molecule inhibitor of soluble epoxide hydrolase (sEH) with IC50 of 7 nM; BI-1935 is also highly active in a cellular Hep G2-DHET assay format with IC50 of <1 nM, BI-1935 can also be used in vivo and showed a dose dependent effect on mean arterial pressure blood pressure in Dahl salt sensitive rats; also shows good selectivity against hCYP epoxygenases 2J2/2C9/2C19 and IL-2. |
| Name | BI-1935 |
|---|
| Description | BI-1935 is a potent, selective small molecule inhibitor of soluble epoxide hydrolase (sEH) with IC50 of 7 nM; BI-1935 is also highly active in a cellular Hep G2-DHET assay format with IC50 of <1 nM, BI-1935 can also be used in vivo and showed a dose dependent effect on mean arterial pressure blood pressure in Dahl salt sensitive rats; also shows good selectivity against hCYP epoxygenases 2J2/2C9/2C19 and IL-2. |
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| References | References View Related Products by Target Other Targets |
| Molecular Formula | C24H21F3N6O3 |
|---|---|
| Molecular Weight | 498.466 |
| InChIKey | KMESAVNRPDKZCQ-UHFFFAOYSA-N |
| SMILES | CCOCCn1cc(C(=O)Nc2ccc(-n3nc(-c4cccnc4)cc3C(F)(F)F)cn2)ccc1=O |