BI-1935

Modify Date: 2024-01-09 12:57:07

BI-1935 Structure
BI-1935 structure
Common Name BI-1935
CAS Number 940954-41-6 Molecular Weight 498.466
Density N/A Boiling Point N/A
Molecular Formula C24H21F3N6O3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of BI-1935


BI-1935 is a potent, selective small molecule inhibitor of soluble epoxide hydrolase (sEH) with IC50 of 7 nM; BI-1935 is also highly active in a cellular Hep G2-DHET assay format with IC50 of <1 nM, BI-1935 can also be used in vivo and showed a dose dependent effect on mean arterial pressure blood pressure in Dahl salt sensitive rats; also shows good selectivity against hCYP epoxygenases 2J2/2C9/2C19 and IL-2.

 Names

Name BI-1935

 BI-1935 Biological Activity

Description BI-1935 is a potent, selective small molecule inhibitor of soluble epoxide hydrolase (sEH) with IC50 of 7 nM; BI-1935 is also highly active in a cellular Hep G2-DHET assay format with IC50 of <1 nM, BI-1935 can also be used in vivo and showed a dose dependent effect on mean arterial pressure blood pressure in Dahl salt sensitive rats; also shows good selectivity against hCYP epoxygenases 2J2/2C9/2C19 and IL-2.
References References View Related Products by Target Other Targets

 Chemical & Physical Properties

Molecular Formula C24H21F3N6O3
Molecular Weight 498.466
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