BI-1935

Names

[ Name ]:
BI-1935

Biological Activity

[Description]:

BI-1935 is a potent, selective small molecule inhibitor of soluble epoxide hydrolase (sEH) with IC50 of 7 nM; BI-1935 is also highly active in a cellular Hep G2-DHET assay format with IC50 of <1 nM, BI-1935 can also be used in vivo and showed a dose dependent effect on mean arterial pressure blood pressure in Dahl salt sensitive rats; also shows good selectivity against hCYP epoxygenases 2J2/2C9/2C19 and IL-2.

[References]

References View Related Products by Target Other Targets

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₄H₂₁F₃N₆O₃

[ Molecular Weight ]:
498.466

Related Compounds

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.