BI 186908
Names
[ CAS No. ]:
1453500-36-1
[ Name ]:
BI 186908
Biological Activity
[Description]:
A potent and selective MCH-R1 antagonist with IC50 of 22 nM, Ki of 14 nM; significantly reduces body weight comparable to sibutramine in a 4 week diet-induced obesity model in rats, possesses favorable DMPK and CMC properties.
[References]
References 1. Oost T, et al. Bioorg Med Chem Lett. 2015 Aug 15;25(16):3275-80. View Related Products by Target Melanin-concentrating Hormone Receptor (MCHR)
Chemical & Physical Properties
[ Molecular Formula ]:
C23H26N4O4
[ Molecular Weight ]:
422.485