IDR-1

Modify Date: 2024-01-30 11:51:54

IDR-1 structure	Common Name	IDR-1
	CAS Number	940291-10-1	Molecular Weight	242.31500
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₆₅H₁₁₈N₁₈O₁₅	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of IDR-1

IDR-1 is an antimicrobial peptide that is active against Gram-positive and Gram-negative bacteria. IDR-1 counters infection by selective modulation of innate immunity without obvious toxicities. IDR-1 has anti-inflammatory and anti-infective properties, enhances the levels of monocyte chemokines, and attenuates pro-inflammatory cytokine release[1][2].

Name	(2S)-1-formyl-N-[(2S)-1-oxopropan-2-yl]pyrrolidine-2-carboxamide,propane
Synonym	More Synonyms

Description	IDR-1 is an antimicrobial peptide that is active against Gram-positive and Gram-negative bacteria. IDR-1 counters infection by selective modulation of innate immunity without obvious toxicities. IDR-1 has anti-inflammatory and anti-infective properties, enhances the levels of monocyte chemokines, and attenuates pro-inflammatory cytokine release[1][2].
Related Catalog	Research Areas >> Infection Research Areas >> Inflammation/Immunology Signaling Pathways >> Anti-infection >> Bacterial
References	[1]. Monisha G Scott, et al. An Anti-Infective Peptide That Selectively Modulates the Innate Immune Response. Nat Biotechnol. 2007 Apr;25(4):465-72. [2]. Man Hou, et al. Antimicrobial Peptide LL-37 and IDR-1 Ameliorate MRSA Pneumonia in Vivo. Cell Physiol Biochem. 2013;32(3):614-23.

Description

Related Catalog

Research Areas >> Infection

Research Areas >> Inflammation/Immunology

Signaling Pathways >> Anti-infection >> Bacterial

References

[1]. Monisha G Scott, et al. An Anti-Infective Peptide That Selectively Modulates the Innate Immune Response. Nat Biotechnol. 2007 Apr;25(4):465-72.

[2]. Man Hou, et al. Antimicrobial Peptide LL-37 and IDR-1 Ameliorate MRSA Pneumonia in Vivo. Cell Physiol Biochem. 2013;32(3):614-23.