IDR-1

Names

[ Name ]:
IDR-1

[Synonym ]:
IDR-1

Biological Activity

[Description]:

IDR-1 is an antimicrobial peptide that is active against Gram-positive and Gram-negative bacteria. IDR-1 counters infection by selective modulation of innate immunity without obvious toxicities. IDR-1 has anti-inflammatory and anti-infective properties, enhances the levels of monocyte chemokines, and attenuates pro-inflammatory cytokine release[1][2].

[Related Catalog]:

Research Areas >> Infection

Research Areas >> Inflammation/Immunology

Signaling Pathways >> Anti-infection >> Bacterial

[References]

[1]. Monisha G Scott, et al. An Anti-Infective Peptide That Selectively Modulates the Innate Immune Response. Nat Biotechnol. 2007 Apr;25(4):465-72.

[2]. Man Hou, et al. Antimicrobial Peptide LL-37 and IDR-1 Ameliorate MRSA Pneumonia in Vivo. Cell Physiol Biochem. 2013;32(3):614-23.

Chemical & Physical Properties

[ Molecular Formula ]:
C₆₅H₁₁₈N₁₈O₁₅

[ Molecular Weight ]:
242.31500

[ Exact Mass ]:
242.16300

[ PSA ]:
69.97000

[ LogP ]:
2.14120

Related Compounds

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.