MDM2-IN-21

Modify Date: 2025-09-21 20:15:00

MDM2-IN-21 Structure
MDM2-IN-21 structure
Common Name MDM2-IN-21
CAS Number 939981-88-1 Molecular Weight 607.61
Density N/A Boiling Point N/A
Molecular Formula C34H40Cl2N4O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of MDM2-IN-21


MDM2-IN-21 is a potent MDM2 inhibitor. MDM2-IN-21 can be used for the research of cancer[1].

 Names

Name MDM2-IN-21

 MDM2-IN-21 Biological Activity

Description MDM2-IN-21 is a potent MDM2 inhibitor. MDM2-IN-21 can be used for the research of cancer[1].
Related Catalog
Target

MDM2[1]

In Vitro The IC50 values of MDM2-IN-21 are 0.03 μM and 0.8 μM in homogeneous time resolved fluorescence (HTRF) assay and the wild-type p53 cell lines[1].
References

[1]. Vu B, et al. Discovery of RG7112: A Small-Molecule MDM2 Inhibitor in Clinical Development. ACS Med Chem Lett. 2013;4(5):466-469.

 Chemical & Physical Properties

Molecular Formula C34H40Cl2N4O2
Molecular Weight 607.61
InChIKey HPHUDNTXCKTLNK-SZAHLOSFSA-N
SMILES CCOc1cc(C(C)(C)C)ccc1C1=NC(C)(c2ccc(Cl)cc2)C(C)(c2ccc(Cl)cc2)N1C(=O)N1CCNCC1
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