HBV-IN-21

Modify Date: 2024-01-13 20:04:41

HBV-IN-21 Structure
HBV-IN-21 structure
Common Name HBV-IN-21
CAS Number 2460957-52-0 Molecular Weight 376.47
Density N/A Boiling Point N/A
Molecular Formula C17H17FN4OS2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of HBV-IN-21


HBV-IN-21 (Compound II-8b) is an HBV DNA replication inhibitor with an IC50 of 2.2 µM. HBV-IN-21 can interact HBV 4 capsid protein with good affinity (KD = 60.0 μM)[1].

 Names

Name HBV-IN-21

 HBV-IN-21 Biological Activity

Description HBV-IN-21 (Compound II-8b) is an HBV DNA replication inhibitor with an IC50 of 2.2 µM. HBV-IN-21 can interact HBV 4 capsid protein with good affinity (KD = 60.0 μM)[1].
Related Catalog
Target

IC50: 2.2 µM (HBV DNA replication)[1]

References

[1]. Jia H, et al. Design, diversity-oriented synthesis and biological evaluation of novel heterocycle derivatives as non-nucleoside HBV capsid protein inhibitors. Eur J Med Chem. 2020 Sep 15;202:112495.

 Chemical & Physical Properties

Molecular Formula C17H17FN4OS2
Molecular Weight 376.47