939981-88-1

939981-88-1 structure
939981-88-1 structure
  • Name: MDM2-IN-21
  • Chemical Name: MDM2-IN-21
  • CAS Number: 939981-88-1
  • Molecular Formula: C34H40Cl2N4O2
  • Molecular Weight: 607.61
  • Catalog: Signaling Pathways Apoptosis MDM-2/p53
  • Create Date: 2021-10-18 20:34:23
  • Modify Date: 2024-01-09 18:14:00
  • MDM2-IN-21 is a potent MDM2 inhibitor. MDM2-IN-21 can be used for the research of cancer[1].

Name MDM2-IN-21
Description MDM2-IN-21 is a potent MDM2 inhibitor. MDM2-IN-21 can be used for the research of cancer[1].
Related Catalog
Target

MDM2[1]

In Vitro The IC50 values of MDM2-IN-21 are 0.03 μM and 0.8 μM in homogeneous time resolved fluorescence (HTRF) assay and the wild-type p53 cell lines[1].
References

[1]. Vu B, et al. Discovery of RG7112: A Small-Molecule MDM2 Inhibitor in Clinical Development. ACS Med Chem Lett. 2013;4(5):466-469.

Molecular Formula C34H40Cl2N4O2
Molecular Weight 607.61
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