pNP-ADPr

Modify Date: 2024-01-02 20:44:49

pNP-ADPr Structure
pNP-ADPr structure
Common Name pNP-ADPr
CAS Number 939028-75-8 Molecular Weight N/A
Density N/A Boiling Point N/A
Molecular Formula C21H26N6O16P2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of pNP-ADPr


pNP-ADPr is a colorimetric substrate that used for the first continuous Poly(ADP-ribose) glycohydrolase (PARG) and ADP-ribosyl hydrolase 3 (ARH3) activity assays. pNP-ADPr can be used for the research of poly(ADP-ribose)polymerase (PARP) enzymes[1][2].

 Names

Name Adenosine 5'-(trihydrogen diphosphate), P'-5-ester with 4-nitrophenyl beta-D-ribofuranoside

 pNP-ADPr Biological Activity

Description pNP-ADPr is a colorimetric substrate that used for the first continuous Poly(ADP-ribose) glycohydrolase (PARG) and ADP-ribosyl hydrolase 3 (ARH3) activity assays. pNP-ADPr can be used for the research of poly(ADP-ribose)polymerase (PARP) enzymes[1][2].
Related Catalog
In Vitro pNP-ADPr is a colorimetric substrate that used for the first continuous Poly(ADP-ribose) glycohydrolase (PARG) and ADP-ribosyl hydrolase 3 (ARH3) activity assays[1].
References

[1]. Drown BS, et al. Monitoring Poly(ADP-ribosyl)glycohydrolase Activity with a Continuous Fluorescent Substrate. Cell Chem Biol. 2018;25(12):1562-1570.e19.

[2]. Nottbohm AC, et al. A colorimetric substrate for poly(ADP-ribose) polymerase-1, VPARP, and tankyrase-1. Angew Chem Int Ed Engl. 2007;46(12):2066-2069.

 Chemical & Physical Properties

Molecular Formula C21H26N6O16P2