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25612-73-1

25612-73-1 structure
25612-73-1 structure
  • Name: Adenylyl Imidodiphosphate
  • Chemical Name: amp-pnp
  • CAS Number: 25612-73-1
  • Molecular Formula: C10H17N6O12P3
  • Molecular Weight: 506.19600
  • Catalog: Research Areas Others
  • Create Date: 2017-08-08 15:53:13
  • Modify Date: 2024-01-10 10:34:43
  • AMP-PNP (Adenylyl imidodiphosphate) is a non-hydrolysable ATP analogue[1].

Name amp-pnp
Synonyms Adenosine beta,gamma-imidotriphosphate
Description AMP-PNP (Adenylyl imidodiphosphate) is a non-hydrolysable ATP analogue[1].
Related Catalog
In Vitro AMP-PNP binding induces an inward rotation and shift of the transmembrane helices of LptFG and LptC to tighten the cavity, with the closure of two lateral gates, to eventually expel LPS into the bridge[1]. AMP-PNP significantly inhibits the ATPase activity of sfLptB2FGC, which was used to mimic and lock an ATP-bound state of sfLptB2FGC[1].
References

[1]. Tang X, et al. Cryo-EM structures of lipopolysaccharide transporter LptB2FGC in lipopolysaccharide or AMP-PNP-bound states reveal its transport mechanism. Nat Commun. 2019 Sep 13;10(1):4175.

Molecular Formula C10H17N6O12P3
Molecular Weight 506.19600
Exact Mass 506.01200
PSA 311.36000