Toll-like receptor modulator

Modify Date: 2025-08-21 15:38:28

Toll-like receptor modulator Structure
Toll-like receptor modulator structure
Common Name Toll-like receptor modulator
CAS Number 926927-42-6 Molecular Weight 348.26800
Density 1.41 g/cm3 Boiling Point 403ºC at 760 mmHg
Molecular Formula C15H13F5N2O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Toll-like receptor modulator


Toll-like receptor modulator is a modulator of TLR7/8, which modulates immune function.

 Names

Name ethyl 2-amino-8-(1,1,2,2,2-pentafluoroethyl)-3H-1-benzazepine-4-carboxylate
Synonym More Synonyms

 Toll-like receptor modulator Biological Activity

Description Toll-like receptor modulator is a modulator of TLR7/8, which modulates immune function.
Related Catalog
Target

TLR7/8[1]

In Vitro Toll-like receptor modulator (Compound 7) is a modulator of TLR7/8, which modulates immune function[1].
References

[1]. Doherty, George A, et al. 8-​substituted benzoazepines as toll-​like receptor modulators. US 8153622 B2.

 Chemical & Physical Properties

Density 1.41 g/cm3
Boiling Point 403ºC at 760 mmHg
Molecular Formula C15H13F5N2O2
Molecular Weight 348.26800
Exact Mass 348.09000
PSA 64.68000
LogP 3.81550
InChIKey ICZPANLPYRTVSF-UHFFFAOYSA-N
SMILES CCOC(=O)C1=Cc2ccc(C(F)(F)C(F)(F)F)cc2N=C(N)C1

 Safety Information

HS Code 2933990090

 Customs

HS Code 2933990090
Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

Ethyl 2-amino-8-(perfluoroethyl)-3H-benzo[b]azepine-4-carboxylate
CS-0290
Toll-like receptor modulator
(1E,4E)-ethyl 2-amino-8-(perfluoroethyl)-3H-benzo[b]azepine-4-carboxylate
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