Toll-like receptor modulator

Names

[ Name ]:
Toll-like receptor modulator

[Synonym ]:
Ethyl 2-amino-8-(perfluoroethyl)-3H-benzo[b]azepine-4-carboxylate
CS-0290
Toll-like receptor modulator
(1E,4E)-ethyl 2-amino-8-(perfluoroethyl)-3H-benzo[b]azepine-4-carboxylate

Biological Activity

[Description]:

Toll-like receptor modulator is a modulator of TLR7/8, which modulates immune function.

[Related Catalog]:

Signaling Pathways >> Immunology/Inflammation >> Toll-like Receptor (TLR)

Research Areas >> Inflammation/Immunology

[Target]

TLR7/8[1]

[In Vitro]

Toll-like receptor modulator (Compound 7) is a modulator of TLR7/8, which modulates immune function[1].

[References]

[1]. Doherty, George A, et al. 8-substituted benzoazepines as toll-like receptor modulators. US 8153622 B2.

[Related Small Molecules]

Chemical & Physical Properties

[ Density]:
1.41 g/cm3

[ Boiling Point ]:
403ºC at 760 mmHg

[ Molecular Formula ]:
C₁₅H₁₃F₅N₂O₂

[ Molecular Weight ]:
348.26800

[ Exact Mass ]:
348.09000

[ PSA ]:
64.68000

[ LogP ]:
3.81550

Safety Information

[ HS Code ]:
2933990090

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%