Cerlapirdine

Modify Date: 2025-09-01 10:31:22

Cerlapirdine Structure
Cerlapirdine structure
Common Name Cerlapirdine
CAS Number 925448-93-7 Molecular Weight 409.50100
Density N/A Boiling Point N/A
Molecular Formula C22H23N3O3S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Cerlapirdine


Cerlapirdine (SAM-531, PF-05212365) is a selective and potent full antagonist of the 5-hydroxytryptamine 6 (5-HT6) receptor. Cerlapirdine has the potential for researching the Alzheimer's disease[1].

 Names

Name N,N-dimethyl-3-[(3-naphthalen-1-ylsulfonyl-2H-indazol-5-yl)oxy]propan-1-amine
Synonym More Synonyms

 Cerlapirdine Biological Activity

Description Cerlapirdine (SAM-531, PF-05212365) is a selective and potent full antagonist of the 5-hydroxytryptamine 6 (5-HT6) receptor. Cerlapirdine has the potential for researching the Alzheimer's disease[1].
Related Catalog
Target

5-HT6 Receptor

References

[1]. Tse S, et al. Disposition and metabolic profiling of [(14)C]cerlapirdine using accelerator mass spectrometry. Drug Metab Dispos. 2014;42(12):2023-2032.

 Chemical & Physical Properties

Molecular Formula C22H23N3O3S
Molecular Weight 409.50100
Exact Mass 409.14600
PSA 83.67000
LogP 4.96020
InChIKey NXQGEDVQXVTCDA-UHFFFAOYSA-N
SMILES CN(C)CCCOc1ccc2n[nH]c(S(=O)(=O)c3cccc4ccccc34)c2c1

 Synonyms

SAM-531
UNII-EK40PJ0V49
Cerlapirdine
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