925448-93-7

925448-93-7 structure

Name: Cerlapirdine
Chemical Name: N,N-dimethyl-3-[(3-naphthalen-1-ylsulfonyl-2H-indazol-5-yl)oxy]propan-1-amine
CAS Number: 925448-93-7
Molecular Formula: C₂₂H₂₃N₃O₃S
Molecular Weight: 409.50100
Catalog: Signaling Pathways GPCR/G Protein 5-HT Receptor
Create Date: 2017-06-27 08:41:00
Modify Date: 2025-09-01 10:31:22
Cerlapirdine (SAM-531, PF-05212365) is a selective and potent full antagonist of the 5-hydroxytryptamine 6 (5-HT6) receptor. Cerlapirdine has the potential for researching the Alzheimer's disease[1].

Name	N,N-dimethyl-3-[(3-naphthalen-1-ylsulfonyl-2H-indazol-5-yl)oxy]propan-1-amine
Synonyms	SAM-531 UNII-EK40PJ0V49 Cerlapirdine

Description	Cerlapirdine (SAM-531, PF-05212365) is a selective and potent full antagonist of the 5-hydroxytryptamine 6 (5-HT6) receptor. Cerlapirdine has the potential for researching the Alzheimer's disease[1].
Related Catalog	Research Areas >> Neurological Disease Signaling Pathways >> GPCR/G Protein >> 5-HT Receptor Signaling Pathways >> Neuronal Signaling >> 5-HT Receptor
Target	5-HT6 Receptor
References	[1]. Tse S, et al. Disposition and metabolic profiling of [(14)C]cerlapirdine using accelerator mass spectrometry. Drug Metab Dispos. 2014;42(12):2023-2032.