PF-3274167

Modify Date: 2025-09-21 13:52:42

PF-3274167 structure	Common Name	PF-3274167
	CAS Number	900510-03-4	Molecular Weight	419.837
	Density	1.4±0.1 g/cm3	Boiling Point	584.0±60.0 °C at 760 mmHg
	Molecular Formula	C₁₉H₁₉ClFN₅O₃	Melting Point	N/A
	MSDS	N/A	Flash Point	307.0±32.9 °C

Use of PF-3274167

Cligosiban (PF-3274167) is a high-affinity nonpeptide oxytocin receptor (OTR) antagonist, with Ki of 9.5 nM.IC50 value: 9.5 nM [1]Target: oxytocin receptor (OTR)

Name	Pyridine, 5-[3-[3-(2-chloro-4-fluorophenoxy)-1-azetidinyl]-5-(methoxymethyl)-4H-1,2,4-triazol-4-yl]-2-methoxy
Synonym	More Synonyms

Description	Cligosiban (PF-3274167) is a high-affinity nonpeptide oxytocin receptor (OTR) antagonist, with Ki of 9.5 nM.IC50 value: 9.5 nM [1]Target: oxytocin receptor (OTR)
Related Catalog	Signaling Pathways >> GPCR/G Protein >> Oxytocin Receptor Research Areas >> Endocrinology
References	[1]. Karpenko IA, et al. Selective nonpeptidic fluorescent ligands for oxytocin receptor: design, synthesis, and application to time-resolved FRET binding assay. J Med Chem. 2015 Mar 12;58(5):2547-2552. [2]. Brown A, et al. Triazole oxytocin antagonists: Identification of an aryloxyazetidine replacement for a biaryl substituent. Bioorg Med Chem Lett. 2010 Jan 15;20(2):516-520.

Description

Cligosiban (PF-3274167) is a high-affinity nonpeptide oxytocin receptor (OTR) antagonist, with Ki of 9.5 nM.IC50 value: 9.5 nM [1]Target: oxytocin receptor (OTR)

Related Catalog

Signaling Pathways >> GPCR/G Protein >> Oxytocin Receptor

Research Areas >> Endocrinology

References

[1]. Karpenko IA, et al. Selective nonpeptidic fluorescent ligands for oxytocin receptor: design, synthesis, and application to time-resolved FRET binding assay. J Med Chem. 2015 Mar 12;58(5):2547-2552.

[2]. Brown A, et al. Triazole oxytocin antagonists: Identification of an aryloxyazetidine replacement for a biaryl substituent. Bioorg Med Chem Lett. 2010 Jan 15;20(2):516-520.

Density	1.4±0.1 g/cm3
Boiling Point	584.0±60.0 °C at 760 mmHg
Molecular Formula	C₁₉H₁₉ClFN₅O₃
Molecular Weight	419.837
Flash Point	307.0±32.9 °C
Exact Mass	419.116058
PSA	74.53000
LogP	1.85
Vapour Pressure	0.0±1.6 mmHg at 25°C
Index of Refraction	1.646

Pyridine, 5-[3-[3-(2-chloro-4-fluorophenoxy)-1-azetidinyl]-5-(methoxymethyl)-4H-1,2,4-triazol-4-yl]-2-methoxy-

pf 3274167

5-{3-[3-(2-Chloro-4-fluorophenoxy)-1-azetidinyl]-5-(methoxymethyl)-4H-1,2,4-triazol-4-yl}-2-methoxypyridine

PF-3274167

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: PF-3274167
Price: Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

ShangHai DC Chemicals Co.,Ltd
China
Product Name: PF-3274167（cligosiban）
Price: ￥Inquiry/1g
Purity: 98.9%
Delivery: 1 Day
Contact: Tony Lai
Email: order@dcchemicals.com

DC Chemicals Limited
China
Product Name: PF-3274167（cligosiban）
Price: $500.0/100mg $900.0/250mg $1900.0/1g
Purity: 98.0%
Delivery: 3 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

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Price: $238/10mM*1mLinDMSO

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PF-3274167

Use of PF-3274167

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PF-3274167 Biological Activity

Chemical & Physical Properties

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The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.