FmocNH-PEG4-t-butyl acetate

Modify Date: 2024-01-07 06:36:46

FmocNH-PEG4-t-butyl acetate structure	Common Name	FmocNH-PEG4-t-butyl acetate
	CAS Number	894427-95-3	Molecular Weight	529.62200
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₉H₃₉NO₈	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of FmocNH-PEG4-t-butyl acetate

FmocNH-PEG4-t-butyl acetate is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	tert-butyl 15-N-(9-fluorenylmethyloxycarbonyl)-15-aza-3,6,9,12-tetraoxa-pentadecanoate
Synonym	More Synonyms

Description	FmocNH-PEG4-t-butyl acetate is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

tert-butyl 5-N-(9-fluorenylmethyloxycarbonyl)-15-aza-3,6,9,12-tetraoxa-pentadecanoate

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