FmocNH-PEG4-t-butyl ester

Modify Date: 2024-01-13 11:12:25

FmocNH-PEG4-t-butyl ester Structure
FmocNH-PEG4-t-butyl ester structure
Common Name FmocNH-PEG4-t-butyl ester
CAS Number 2148295-94-5 Molecular Weight 543.65
Density N/A Boiling Point N/A
Molecular Formula C30H41NO8 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of FmocNH-PEG4-t-butyl ester


FmocNH-PEG4-t-butyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name FmocNH-PEG4-t-butyl ester

 FmocNH-PEG4-t-butyl ester Biological Activity

Description FmocNH-PEG4-t-butyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C30H41NO8
Molecular Weight 543.65