Rhodblock 6

Modify Date: 2024-01-10 17:20:09

Rhodblock 6 Structure
Rhodblock 6 structure
Common Name Rhodblock 6
CAS Number 886625-06-5 Molecular Weight 215.25
Density N/A Boiling Point N/A
Molecular Formula C12H13N3O Melting Point N/A
MSDS Chinese USA Flash Point N/A
Symbol GHS07
GHS07
Signal Word Warning

 Use of Rhodblock 6


Rhodblock 6 is a Rho kinase (ROCK) inhibitor that inhibits phospho-MRLC (myosin regulatory light chain) localization[1].

 Names

Name N-(1H-indazol-5-yl)cyclobutanecarboxamide
Synonym More Synonyms

 Rhodblock 6 Biological Activity

Description Rhodblock 6 is a Rho kinase (ROCK) inhibitor that inhibits phospho-MRLC (myosin regulatory light chain) localization[1].
Related Catalog
References

[1]. Adam B Castoreno, et al. Small molecules discovered in a pathway screen target the Rho pathway in cytokinesis. Nat Chem Biol. 2010 Jun;6(6):457-63.  

 Chemical & Physical Properties

Molecular Formula C12H13N3O
Molecular Weight 215.25
Exact Mass 215.10600
PSA 57.78000
LogP 2.37450

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H302
RIDADR NONH for all modes of transport

 Articles1

More Articles
Ventromedial hypothalamic nitric oxide production is necessary for hypoglycemia detection and counterregulation.

Diabetes 59 , 519-28, (2010)

The response of ventromedial hypothalamic (VMH) glucose-inhibited neurons to decreased glucose is impaired under conditions where the counterregulatory response (CRR) to hypoglycemia is impaired (e.g....

 Synonyms

Rhodblock 6
HMS2849B12
HMS3260N15
HMS1606O05