Ceratotoxin-2

Modify Date: 2024-01-29 19:00:10

Ceratotoxin-2 structure	Common Name	Ceratotoxin-2
	CAS Number	880885-98-3	Molecular Weight	4092.67
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₇₇H₂₆₀N₅₂O₄₉S₆	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Ceratotoxin-2

Ceratotoxin-2 (CcoTx2) is a voltage-gated sodium channel blocker with IC50s of 8 nM and 88 nM against Nav1.2/β1 and Nav1.3/β1, respectively[1].

Name	Ceratotoxin-2

Description	Ceratotoxin-2 (CcoTx2) is a voltage-gated sodium channel blocker with IC50s of 8 nM and 88 nM against Nav1.2/β1 and Nav1.3/β1, respectively[1].
Related Catalog	Signaling Pathways >> Membrane Transporter/Ion Channel >> Sodium Channel Research Areas >> Neurological Disease
Target	IC50: 8 nM (Nav1.2/β1), 88 nM (Nav1.3/β1), 400 nM (Nav1.4/β1), 407 nM (Nav1.1/β1), 1634 nM (Nav1.5/β1)[1]
References	[1]. Bosmans F, et al. Four novel tarantula toxins as selective modulators of voltage-gated sodium channel subtypes. Mol Pharmacol. 2006 Feb;69(2):419-29.

Molecular Formula	C₁₇₇H₂₆₀N₅₂O₄₉S₆
Molecular Weight	4092.67

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