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880885-98-3

880885-98-3 structure

880885-98-3 structure

Name: Ceratotoxin-2
Chemical Name: Ceratotoxin-2
CAS Number: 880885-98-3
Molecular Formula: C₁₇₇H₂₆₀N₅₂O₄₉S₆
Molecular Weight: 4092.67
Catalog: Signaling Pathways Membrane Transporter/Ion Channel Sodium Channel
Create Date: 2023-11-26 18:35:15
Modify Date: 2024-01-29 19:00:10
Ceratotoxin-2 (CcoTx2) is a voltage-gated sodium channel blocker with IC50s of 8 nM and 88 nM against Nav1.2/β1 and Nav1.3/β1, respectively[1].

Name	Ceratotoxin-2

Description	Ceratotoxin-2 (CcoTx2) is a voltage-gated sodium channel blocker with IC50s of 8 nM and 88 nM against Nav1.2/β1 and Nav1.3/β1, respectively[1].
Related Catalog	Signaling Pathways >> Membrane Transporter/Ion Channel >> Sodium Channel Research Areas >> Neurological Disease
Target	IC50: 8 nM (Nav1.2/β1), 88 nM (Nav1.3/β1), 400 nM (Nav1.4/β1), 407 nM (Nav1.1/β1), 1634 nM (Nav1.5/β1)[1]
References	[1]. Bosmans F, et al. Four novel tarantula toxins as selective modulators of voltage-gated sodium channel subtypes. Mol Pharmacol. 2006 Feb;69(2):419-29.

Molecular Formula	C₁₇₇H₂₆₀N₅₂O₄₉S₆
Molecular Weight	4092.67

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