Delta-12-Prostaglandin J2
Modify Date: 2025-08-25 17:13:07
Delta-12-Prostaglandin J2 structure
|
Common Name | Delta-12-Prostaglandin J2 | ||
|---|---|---|---|---|
| CAS Number | 87893-54-7 | Molecular Weight | 334.450 | |
| Density | 1.1±0.1 g/cm3 | Boiling Point | 531.2±50.0 °C at 760 mmHg | |
| Molecular Formula | C20H30O4 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 289.2±26.6 °C | |
Use of Delta-12-Prostaglandin J2Delta-12-Prostaglandin J2 (Δ12-PGJ2) is a cyclopentenone prostaglandin (PG) with anti-proliferative effect on various tumor cell growth. Delta-12-Prostaglandin J2, a naturally occurring dehydration product of prostaglandin D2, is able to induce apoptosis in HeLa cells via caspase activation[1][2]. |
| Name | 13,14-dihydro-Δ12-prostaglandin J2 |
|---|---|
| Synonym | More Synonyms |
| Description | Delta-12-Prostaglandin J2 (Δ12-PGJ2) is a cyclopentenone prostaglandin (PG) with anti-proliferative effect on various tumor cell growth. Delta-12-Prostaglandin J2, a naturally occurring dehydration product of prostaglandin D2, is able to induce apoptosis in HeLa cells via caspase activation[1][2]. |
|---|---|
| Related Catalog | |
| Target |
Human Endogenous Metabolite |
| References |
| Density | 1.1±0.1 g/cm3 |
|---|---|
| Boiling Point | 531.2±50.0 °C at 760 mmHg |
| Molecular Formula | C20H30O4 |
| Molecular Weight | 334.450 |
| Flash Point | 289.2±26.6 °C |
| Exact Mass | 334.214417 |
| PSA | 74.60000 |
| LogP | 4.12 |
| Vapour Pressure | 0.0±3.2 mmHg at 25°C |
| Index of Refraction | 1.558 |
| InChIKey | TUXFWOHFPFBNEJ-GJGHEGAFSA-N |
| SMILES | CCCCCC(O)CC=C1C(=O)C=CC1CC=CCCCC(=O)O |
| 12-PROSTAGLANDIN J2 |
| (5Z,12E,15S)-15-Hydroxy-11-oxoprosta-5,9,12-trien-1-oic acid |
| (5Z,12E,15S)-11-Oxo-15-hydroxyprosta-5,9,12-triene-1-oic acid |
| DELTA12-PGJ2 |
| Prosta-5,9,12-trien-1-oic acid, 15-hydroxy-11-oxo-, (5Z,12E,15S)- |
| 11-OXO-15S-HYDROXY-PROSTA-5Z,9,12E-TRIEN-1-OIC ACID |
| 13,14-dihydro-Delta(12)-prostaglandin J2 |
| 13,14-dihydro-δ(12)-prostaglandin J2 |
| DELTA12-PROSTAGLANDIN J2 |
| 9-deoxy-9,10-didehydro-12,13-didehydro-13,14-dihydroprostaglandin D2 |