87893-54-7
87893-54-7 structure
- Name: Delta-12-Prostaglandin J2
- Chemical Name: 13,14-dihydro-Δ12-prostaglandin J2
- CAS Number: 87893-54-7
- Molecular Formula: C20H30O4
- Molecular Weight: 334.450
- Catalog: Signaling Pathways Apoptosis Apoptosis
- Create Date: 2016-03-07 16:05:38
- Modify Date: 2024-01-13 20:20:42
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Delta-12-Prostaglandin J2 (Δ12-PGJ2) is a cyclopentenone prostaglandin (PG) with anti-proliferative effect on various tumor cell growth. Delta-12-Prostaglandin J2, a naturally occurring dehydration product of prostaglandin D2, is able to induce apoptosis in HeLa cells via caspase activation[1][2].
| Name | 13,14-dihydro-Δ12-prostaglandin J2 |
|---|---|
| Synonyms |
12-PROSTAGLANDIN J2
(5Z,12E,15S)-15-Hydroxy-11-oxoprosta-5,9,12-trien-1-oic acid (5Z,12E,15S)-11-Oxo-15-hydroxyprosta-5,9,12-triene-1-oic acid DELTA12-PGJ2 Prosta-5,9,12-trien-1-oic acid, 15-hydroxy-11-oxo-, (5Z,12E,15S)- 11-OXO-15S-HYDROXY-PROSTA-5Z,9,12E-TRIEN-1-OIC ACID 13,14-dihydro-Delta(12)-prostaglandin J2 13,14-dihydro-δ(12)-prostaglandin J2 DELTA12-PROSTAGLANDIN J2 9-deoxy-9,10-didehydro-12,13-didehydro-13,14-dihydroprostaglandin D2 |
| Description | Delta-12-Prostaglandin J2 (Δ12-PGJ2) is a cyclopentenone prostaglandin (PG) with anti-proliferative effect on various tumor cell growth. Delta-12-Prostaglandin J2, a naturally occurring dehydration product of prostaglandin D2, is able to induce apoptosis in HeLa cells via caspase activation[1][2]. |
|---|---|
| Related Catalog | |
| Target |
Human Endogenous Metabolite |
| References |
| Density | 1.1±0.1 g/cm3 |
|---|---|
| Boiling Point | 531.2±50.0 °C at 760 mmHg |
| Molecular Formula | C20H30O4 |
| Molecular Weight | 334.450 |
| Flash Point | 289.2±26.6 °C |
| Exact Mass | 334.214417 |
| PSA | 74.60000 |
| LogP | 4.12 |
| Vapour Pressure | 0.0±3.2 mmHg at 25°C |
| Index of Refraction | 1.558 |