LY2183240 structure
|
Common Name | LY2183240 | ||
---|---|---|---|---|
CAS Number | 874902-19-9 | Molecular Weight | 307.350 | |
Density | 1.2±0.1 g/cm3 | Boiling Point | 506.1±53.0 °C at 760 mmHg | |
Molecular Formula | C17H17N5O | Melting Point | 87-88ºC | |
MSDS | N/A | Flash Point | 259.9±30.9 °C |
Use of LY2183240LY2183240 is a novel and highly potent blocker of anandamide uptake (IC50 = 270 pM). LY2183240 inhibits fatty acid amide hydrolase (FAAH) activity (IC50 = 12.4 nM). IC50: 270 pM (anandamide uptake); 12.4 nM (FAAH)Target: FAAH; Anandamide uptakeFollowing i.p. administration in rats, LY2183240 increases brain anandamide concentration and exerts antinociceptive effects in formalin model of pain. |
Name | N,N-dimethyl-5-[(4-phenylphenyl)methyl]tetrazole-1-carboxamide |
---|---|
Synonym | More Synonyms |
Description | LY2183240 is a novel and highly potent blocker of anandamide uptake (IC50 = 270 pM). LY2183240 inhibits fatty acid amide hydrolase (FAAH) activity (IC50 = 12.4 nM). IC50: 270 pM (anandamide uptake); 12.4 nM (FAAH)Target: FAAH; Anandamide uptakeFollowing i.p. administration in rats, LY2183240 increases brain anandamide concentration and exerts antinociceptive effects in formalin model of pain. |
---|---|
Related Catalog | |
References |
Density | 1.2±0.1 g/cm3 |
---|---|
Boiling Point | 506.1±53.0 °C at 760 mmHg |
Melting Point | 87-88ºC |
Molecular Formula | C17H17N5O |
Molecular Weight | 307.350 |
Flash Point | 259.9±30.9 °C |
Exact Mass | 307.143311 |
PSA | 63.91000 |
LogP | 2.15 |
Vapour Pressure | 0.0±1.3 mmHg at 25°C |
Index of Refraction | 1.640 |
Storage condition | 2-8℃ |
Risk Phrases | 22 |
---|
5-(4-Biphenylylmethyl)-N,N-dimethyl-1H-tetrazole-1-carboxamide |
LY-2183240 |
HMS3269E15 |
1H-Tetrazole-1-carboxamide |
1H-Tetrazole-1-carboxamide, 5-([1,1'-biphenyl]-4-ylmethyl)-N,N-dimethyl- |
5-(Biphenyl-4-ylmethyl)-N,N-dimethyl-1H-tetrazole-1-carboxamide |
LY2183240 |