L-741,742 hydrochloride

Modify Date: 2025-08-20 13:17:55

L-741,742 hydrochloride Structure
L-741,742 hydrochloride structure
 Common Name L-741,742 hydrochloride
CAS Number 874882-93-6 Molecular Weight 417.37
Density N/A Boiling Point N/A
Molecular Formula C23H26Cl2N2O Melting Point N/A
MSDS N/A Flash Point N/A

 Use of L-741,742 hydrochloride


L 741742 hydrochloride is an orally active and selective antagonist of hD4 receptors. L 741742 hydrochloride has a good brain penetration. L 741742 hydrochloride can be used in study nervous system disorders, particularly schizophrenia[1].

 Names

Name Piperidine, 4-[5-(4-chlorophenyl)-4-methyl-3-isoxazolyl]-1-(2-phenylethyl)-, hydrochloride
Synonym More Synonyms

 L-741,742 hydrochloride Biological Activity

Description L 741742 hydrochloride is an orally active and selective antagonist of hD4 receptors. L 741742 hydrochloride has a good brain penetration. L 741742 hydrochloride can be used in study nervous system disorders, particularly schizophrenia[1].
Related Catalog
References

[1]. Rowley M, et al. 4-Heterocyclylpiperidines as selective high-affinity ligands at the human dopamine D4 receptor. J Med Chem. 1997 Jul 18;40(15):2374-85.  

 Chemical & Physical Properties

Molecular Formula C23H26Cl2N2O
Molecular Weight 417.37
Exact Mass 416.14200
PSA 29.27000
LogP 6.46540
InChIKey HZRPUQURUAXOHB-UHFFFAOYSA-N
SMILES Cc1c(C2CCN(CCc3ccccc3)CC2)noc1-c1ccc(Cl)cc1.Cl

 Synonyms

Methimepip dihydrobromide
L-741,742 hydrochloride
Piperidine, 4-[5-(4-chlorophenyl)-4-methyl-3-isoxazolyl]-1-(2-phenylethyl)-, monohydrochloride
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