874882-93-6

874882-93-6 structure

Name: L-741,742 hydrochloride
Chemical Name: Piperidine, 4-[5-(4-chlorophenyl)-4-methyl-3-isoxazolyl]-1-(2-phenylethyl)-, hydrochloride
CAS Number: 874882-93-6
Molecular Formula: C₂₃H₂₆Cl₂N₂O
Molecular Weight: 417.37
Catalog: Signaling Pathways GPCR/G Protein Dopamine Receptor
Create Date: 2017-12-15 07:35:24
Modify Date: 2025-08-20 13:17:55
L 741742 hydrochloride is an orally active and selective antagonist of hD4 receptors. L 741742 hydrochloride has a good brain penetration. L 741742 hydrochloride can be used in study nervous system disorders, particularly schizophrenia[1].

Name	Piperidine, 4-[5-(4-chlorophenyl)-4-methyl-3-isoxazolyl]-1-(2-phenylethyl)-, hydrochloride
Synonyms	Methimepip dihydrobromide L-741,742 hydrochloride Piperidine, 4-[5-(4-chlorophenyl)-4-methyl-3-isoxazolyl]-1-(2-phenylethyl)-, monohydrochloride

Description	L 741742 hydrochloride is an orally active and selective antagonist of hD4 receptors. L 741742 hydrochloride has a good brain penetration. L 741742 hydrochloride can be used in study nervous system disorders, particularly schizophrenia[1].
Related Catalog	Signaling Pathways >> GPCR/G Protein >> Dopamine Receptor Signaling Pathways >> Neuronal Signaling >> Dopamine Receptor Research Areas >> Neurological Disease
References	[1]. Rowley M, et al. 4-Heterocyclylpiperidines as selective high-affinity ligands at the human dopamine D4 receptor. J Med Chem. 1997 Jul 18;40(15):2374-85.