Indomethacin-D4
Modify Date: 2024-01-23 16:54:06
Indomethacin-D4 structure
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Common Name | Indomethacin-D4 | ||
|---|---|---|---|---|
| CAS Number | 87377-08-0 | Molecular Weight | 361.81200 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C19H12D4ClNO4 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Indomethacin-D4Indomethacin-D4 (Indometacin-D4) is a deuterium labeled Indomethacin. Indomethacin is a potent and nonselective inhibitor of COX1 and COX2, with IC50s of 18 nM and 26 nM for human COX-1 and COX-2, respectively, in CHO cells[1]. |
| Name | 1-(-p-chlorobenzoyl)-2-methyl-5-methoxy-3-indolylacetic acid-d4 |
|---|
| Description | Indomethacin-D4 (Indometacin-D4) is a deuterium labeled Indomethacin. Indomethacin is a potent and nonselective inhibitor of COX1 and COX2, with IC50s of 18 nM and 26 nM for human COX-1 and COX-2, respectively, in CHO cells[1]. |
|---|---|
| Related Catalog | |
| Target |
Human COX-1:18 nM (IC50, in CHO cells) Human COX-2:26 nM (IC50, in CHO cells) |
| References |
| Molecular Formula | C19H12D4ClNO4 |
|---|---|
| Molecular Weight | 361.81200 |
| Exact Mass | 361.10200 |
| PSA | 68.53000 |
| LogP | 3.92730 |