SID 7969543
Modify Date: 2025-08-27 08:39:59
SID 7969543 structure
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Common Name | SID 7969543 | ||
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| CAS Number | 868224-64-0 | Molecular Weight | 452.45700 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C24H24N2O7 | Melting Point | N/A | |
| MSDS | USA | Flash Point | N/A | |
Use of SID 7969543SID 7969543 is a selective SF-1 (steroidogenic factor 1, NR5A1) inhibitor with an IC50 of 760 nM. SID 7969543 inhibits SF-1-triggered luciferase expression with IC50 of 30 nM. SF-1 is a transcription factor belonging to the nuclear receptor superfamily[1][2]. |
| Name | ethyl 2-[2-[2-(2,3-dihydro-1,4-benzodioxin-6-ylamino)-2-oxoethyl]-1-oxoisoquinolin-5-yl]oxypropanoate |
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| Synonym | More Synonyms |
| Description | SID 7969543 is a selective SF-1 (steroidogenic factor 1, NR5A1) inhibitor with an IC50 of 760 nM. SID 7969543 inhibits SF-1-triggered luciferase expression with IC50 of 30 nM. SF-1 is a transcription factor belonging to the nuclear receptor superfamily[1][2]. |
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| Related Catalog | |
| In Vitro | SID 7969543 shows IC50s of >33,333 nM for RORα, VP-16, respectively[1]. SID 7969543 is assayed for functional activity against HEK 293T cells co-transfected with a plasmid encoding full length SF-1 and a second vector allowing expression of the luciferase gene under control of five tandem repeats of the natural SF-1 response element (SFRE). SID 7969543 inhibits SF-1-triggered luciferase expression with IC50 values of 30 ± 15 nM[1]. |
| References |
| Molecular Formula | C24H24N2O7 |
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| Molecular Weight | 452.45700 |
| Exact Mass | 452.15800 |
| PSA | 105.09000 |
| LogP | 2.81480 |
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
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| Hazard Codes | Xi |
| RIDADR | NONH for all modes of transport |
| Precursor 1 | |
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| DownStream 0 | |
| F1808-0160 |
| isoquinolinone scaffold,2 |