Cyclo(-Arg-Gly-Asp-D-Phe-Cys) acetate salt

Modify Date: 2024-01-13 13:52:32

Cyclo(-Arg-Gly-Asp-D-Phe-Cys) acetate salt structure	Common Name	Cyclo(-Arg-Gly-Asp-D-Phe-Cys) acetate salt
	CAS Number	862772-11-0	Molecular Weight	578.64100
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₄H₃₄N₈O₇S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Cyclo(-Arg-Gly-Asp-D-Phe-Cys) acetate salt

Cyclo(Arg-Gly-Asp-D-Phe-Cys) (Cyclo RGDfC) is a cyclic RGD peptide which has high affinity to αvβ3. Cyclo(Arg-Gly-Asp-D-Phe-Cys) can be used in the research of tumors[1].

Name	Cyclo(L-arginylglycyl-L-α-aspartyl-D-phenylalanyl-L-cysteinyl)
Synonym	More Synonyms

Description	Cyclo(Arg-Gly-Asp-D-Phe-Cys) (Cyclo RGDfC) is a cyclic RGD peptide which has high affinity to αvβ3. Cyclo(Arg-Gly-Asp-D-Phe-Cys) can be used in the research of tumors[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cytoskeleton >> Integrin
Target	αvβ3
In Vitro	Cyclo(Arg-Gly-Asp-D-Phe-Cys) (0.5 mM, 24 h) down-regulates the transcription factors Oct 4, Sox 2 and Nanog of mESCs[1]. Cyclo(Arg-Gly-Asp-D-Phe-Cys) (0.5 mM) inhibits integrin gene expression mESC-col I (type I collagen) constructs[1]. Cyclo(Arg-Gly-Asp-D-Phe-Cys) (0.5 mM)-treated mESCs leads to the formation of aggregates and detachment from the surface[1]. RT-PCR[1] Cell Line: MESCs Concentration: 0.5 mM Incubation Time: 24 h Result: Down-regulated Oct 4, Nanog, Sox 2 by 99%, 97.5%, and 90% respectively. Up-regulated Rex1 gene expression.
In Vivo	Cyclo(Arg-Gly-Asp-D-Phe-Cys) (0.5 mM, 24 h)-treated mESCs in the presence/absence of LIF (injected in both thighs) generated teratomas in severe combined immunodeficiency (SCID) mice, which indicates that the process of mESC tumor formation in vivo is dependent on integrin interaction[1].

Molecular Formula	C₂₄H₃₄N₈O₇S
Molecular Weight	578.64100
Exact Mass	578.22700
PSA	283.50000

cyclo (Arg-Gly-Asp-d-Phe-Cys)

CYCLO(ARG-GLY-ASP-D-PHE-CYS)ACETATE SALT

cyclo(Arg-Gly-Asp-d-Phe-Cys)

Cyclo(-RGDfC), avb3 Integrin Binding Cyclic RGD Peptide

CYCLO(-ARG-GLY-ASP-D-PHE-CYS)

GL Biochem (Shanghai) Ltd.
China
Product Name: cyclo (Arg-Gly-Asp-d-Phe-Cys)
Price: $Inquiry/1g
Purity: 98.0%
Stocking Period: Inquiry
Contact: Jackie Yang

DC Chemicals Limited
China
Product Name: Cyclo(RGDfC)
Price: $650.0/100mg $1100.0/250mg $2300.0/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Cyclo(-Arg-Gly-Asp-D-Phe-Cys)
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

Zhejiang Hangyu API Co., Ltd
China
Product Name: c(RGDfC)
Price: $Inquiry/1kg
Purity: 99.0%
Stocking Period: 1 Day
Contact: Vinnie

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