Cyclo(-Arg-Gly-Asp-D-Phe-Lys) trifluoroacetate salt
Modify Date: 2024-01-02 20:14:29
Cyclo(-Arg-Gly-Asp-D-Phe-Lys) trifluoroacetate salt structure
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Common Name | Cyclo(-Arg-Gly-Asp-D-Phe-Lys) trifluoroacetate salt | ||
|---|---|---|---|---|
| CAS Number | 161552-03-0 | Molecular Weight | 603.670 | |
| Density | 1.5±0.1 g/cm3 | Boiling Point | N/A | |
| Molecular Formula | C27H41N9O7 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Cyclo(-Arg-Gly-Asp-D-Phe-Lys) trifluoroacetate saltCyclo(-RGDfK) is a potent and selective inhibitor of the αvβ3 integrin, with an IC50 of 0.94 nM. Sequence: Cyclo(Arg-Gly-Asp-Phe-Lys). |
| Name | 2-[(2S,5R,8S,11S)-8-(4-aminobutyl)-5-benzyl-11-[3-(diaminomethylideneamino)propyl]-3,6,9,12,15-pentaoxo-1,4,7,10,13-pentazacyclopentadec-2-yl]acetic acid |
|---|---|
| Synonym | More Synonyms |
| Description | Cyclo(-RGDfK) is a potent and selective inhibitor of the αvβ3 integrin, with an IC50 of 0.94 nM. Sequence: Cyclo(Arg-Gly-Asp-Phe-Lys). |
|---|---|
| Related Catalog | |
| Target |
IC50: 0.94 nM (αvβ3 integrin)[1]. |
| In Vitro | Cyclo(-RGDfK) is a potent and selective inhibitor of the αvβ3 integrin, with a IC50 of 0.94 nM[1]. [(66)Ga]DOTA-E-[c(RGDfK)]2 can be prepared with high radiochemical purity (>97%), specific activity (36-67GBq/μM), in vitro stability, and moderate protein binding. MicroPET imaging up to 24 post-injection showed contrasting tumors reflecting αvβ3-targeted tracer accumulation[2]. |
| References |
| Density | 1.5±0.1 g/cm3 |
|---|---|
| Molecular Formula | C27H41N9O7 |
| Molecular Weight | 603.670 |
| Exact Mass | 603.312866 |
| PSA | 288.17000 |
| LogP | -3.10 |
| Index of Refraction | 1.666 |
| Storage condition | -20°C |
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Cyclo(-Arg-Gly-... CAS#:161552-03-0 |
| Literature: Petersen, Svea; Alonso, Jose Maria; Specht, Alexandre; Duodu, Portia; Goeldner, Maurice; Del Campo, Aranzazu Angewandte Chemie - International Edition, 2008 , vol. 47, # 17 p. 3192 - 3195 |
|
~%
Cyclo(-Arg-Gly-... CAS#:161552-03-0 |
| Literature: Boturyn, Didier; Dumy, Pascal Tetrahedron Letters, 2001 , vol. 42, # 15 p. 2787 - 2790 |
|
~%
Cyclo(-Arg-Gly-... CAS#:161552-03-0 |
| Literature: Boturyn, Didier; Dumy, Pascal Tetrahedron Letters, 2001 , vol. 42, # 15 p. 2787 - 2790 |
|
~%
Cyclo(-Arg-Gly-... CAS#:161552-03-0 |
| Literature: Boturyn, Didier; Dumy, Pascal Tetrahedron Letters, 2001 , vol. 42, # 15 p. 2787 - 2790 |
|
~%
Cyclo(-Arg-Gly-... CAS#:161552-03-0 |
| Literature: Boturyn, Didier; Dumy, Pascal Tetrahedron Letters, 2001 , vol. 42, # 15 p. 2787 - 2790 |
| Cyclo (-RGDfK) |
| c(D-Phe-Lys-Arg-Gly-Asp) |
| A8164 |
| Cyclo(L-arginylglycyl-L-α-aspartyl-D-phenylalanyl-L-lysyl) |
| cyclo-[Arg-Gly-Asp-D-Phe-Lys] |
| Cyclo[L-α-aspartyl-D-phenylalanyl-L-lysyl-N-(diaminomethylene)-L-ornithylglycyl] |
| cyclic-RGD peptide |
| cyclo[RGD-{D-F}-K] |
| cyclo(RGDfK) |
| Cyclo-RGDfK |
- DC Chemicals Limited
- China
- Product Name: cyclo(-RGDfK)
- Price: $500.0/100mg $950.0/250mg $1800.0/1g
- Purity: 98.0%
- Stocking Period: 3 Day
- Contact: Tony Cao
- Nanjing Peptide Biotech Ltd
- China
- Product Name: Cyclo(RGDfK)
- Price: ￥Inquiry/10g ￥Inquiry/100g ￥Inquiry/1kg ￥Inquiry/10kg
- Purity: 98.0%
- Stocking Period: 7 Day
- Contact: jom
- Zhejiang Hangyu API Co., Ltd
- China
- Product Name: c(RGDfK)
- Price: $Inquiry/1kg
- Purity: 99.0%
- Stocking Period: 1 Day
- Contact: Vinnie
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Price: $185/10mM*1mLinDMSO
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