Cyclo [Arg-Gly-Asp-D-Phe-Val]

Modify Date: 2025-08-26 16:01:43

Cyclo [Arg-Gly-Asp-D-Phe-Val] structure	Common Name	Cyclo [Arg-Gly-Asp-D-Phe-Val]
	CAS Number	137813-35-5	Molecular Weight	574.62900
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₆H₃₈N₈O₇	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Cyclo [Arg-Gly-Asp-D-Phe-Val]

Cyclo(Arg-Gly-Asp-D-Phe-Val) is an integrin αvβ3 inhibitor. Cyclo(Arg-Gly-Asp-D-Phe-Val) has antitumor activity. Cyclo(Arg-Gly-Asp-D-Phe-Val) can be used for the research of acute myeloid leukemia[1].

Name	cyclo(arg-gly-asp-d-phe-val)
Synonym	More Synonyms

Description	Cyclo(Arg-Gly-Asp-D-Phe-Val) is an integrin αvβ3 inhibitor. Cyclo(Arg-Gly-Asp-D-Phe-Val) has antitumor activity. Cyclo(Arg-Gly-Asp-D-Phe-Val) can be used for the research of acute myeloid leukemia[1].
Related Catalog	Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Cancer Signaling Pathways >> Cytoskeleton >> Integrin
Target	αvβ3[1]
In Vitro	Cyclo(Arg-Gly-Asp-d-Phe-Val) (c(RGDfV)) (35 nM, 4-24 h) disruptes the adhesion and migration between the tumor cells and the matrix, induces the leukemia cells to leave the protective microenvironment and increases their sensitivity to cell cycle-dependent agents[1]. Cell Cycle Analysis[1] Cell Line: MV4–11 cells Concentration: 35 nM Incubation Time: 24 h Result: Affected the leukemia cell cycle, decreased the G0/G1 phase of leukemia cells in the 3D and 2D culture systems and increased the S phase of leukemia cells in the 3D and 2D culture systems. Apoptosis Analysis[1] Cell Line: MV4–11 cells Concentration: 35 nM Incubation Time: 24 h Result: Increased the apoptosis rates.

Molecular Formula	C₂₆H₃₈N₈O₇
Molecular Weight	574.62900
Exact Mass	574.28600
PSA	244.70000
LogP	0.52700

RGDFV PEPTIDE,CYCLIC

Cyclo(Arg-Gly-Asp-D-Phe-Val)

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Cyclo [Arg-Gly-Asp-D-Phe-Val] Biological Activity

Chemical & Physical Properties

Synonyms

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.