NPD4456

Modify Date: 2025-08-27 20:00:44

NPD4456 Structure
NPD4456 structure
Common Name NPD4456
CAS Number 859668-98-7 Molecular Weight 383.395
Density 1.3±0.1 g/cm3 Boiling Point 568.8±50.0 °C at 760 mmHg
Molecular Formula C21H21NO6 Melting Point N/A
MSDS Chinese USA Flash Point 297.8±30.1 °C
Symbol GHS09
GHS09
Signal Word Warning

 Use of NPD4456


A coumarin-based HIV-1 viral protein R (Vpr) inhibitor, inhibits Vpr-dependent viral infection of human macrophages.

 Names

Name NPD4456
Synonym More Synonyms

 NPD4456 Biological Activity

Description A coumarin-based HIV-1 viral protein R (Vpr) inhibitor, inhibits Vpr-dependent viral infection of human macrophages.
References References 1. Ong EB, et al. J Biol Chem. 2011 Apr 22;286(16):14049-56. View Related Products by Target HIV

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 568.8±50.0 °C at 760 mmHg
Molecular Formula C21H21NO6
Molecular Weight 383.395
Flash Point 297.8±30.1 °C
Exact Mass 383.136902
LogP 3.94
Vapour Pressure 0.0±1.6 mmHg at 25°C
Index of Refraction 1.579

 Safety Information

Symbol GHS09
GHS09
Signal Word Warning
Hazard Statements H400
Precautionary Statements P273
RIDADR UN 3077 9 / PGIII

 Synonyms

Carbamic acid, N,N-dimethyl-, 3-(2,5-dimethoxyphenyl)-4-methyl-2-oxo-2H-1-benzopyran-7-yl ester
MFCD06765007
NPD4456
Dimethyl-carbamic acid 3-(2,5-dimethoxyphenyl)-4-methyl-2-oxo-2H-1-benzopyran-7-yl ester (9CI)
3-(2,5-Dimethoxyphenyl)-4-methyl-2-oxo-2H-chromen-7-yl dimethylcarbamate
RIKEN Natural Product Derivative (NPD) 4456
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