NPD4456

Names

[ Name ]:
NPD4456

[Synonym ]:
Carbamic acid, N,N-dimethyl-, 3-(2,5-dimethoxyphenyl)-4-methyl-2-oxo-2H-1-benzopyran-7-yl ester
MFCD06765007
NPD4456
Dimethyl-carbamic acid 3-(2,5-dimethoxyphenyl)-4-methyl-2-oxo-2H-1-benzopyran-7-yl ester (9CI)
3-(2,5-Dimethoxyphenyl)-4-methyl-2-oxo-2H-chromen-7-yl dimethylcarbamate
RIKEN Natural Product Derivative (NPD) 4456

Biological Activity

[Description]:

A coumarin-based HIV-1 viral protein R (Vpr) inhibitor, inhibits Vpr-dependent viral infection of human macrophages.

[References]

References 1. Ong EB, et al. J Biol Chem. 2011 Apr 22;286(16):14049-56. View Related Products by Target HIV

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
568.8±50.0 °C at 760 mmHg

[ Molecular Formula ]:
C₂₁H₂₁NO₆

[ Molecular Weight ]:
383.395

[ Flash Point ]:
297.8±30.1 °C

[ Exact Mass ]:
383.136902

[ LogP ]:
3.94

[ Vapour Pressure ]:
0.0±1.6 mmHg at 25°C

[ Index of Refraction ]:
1.579

Safety Information

[ Symbol ]:

GHS09

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H400

[ Precautionary Statements ]:
P273

[ RIDADR ]:
UN 3077 9 / PGIII

Related Compounds

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