859668-98-7
859668-98-7 structure
- Name: NPD4456
- Chemical Name: NPD4456
- CAS Number: 859668-98-7
- Molecular Formula: C21H21NO6
- Molecular Weight: 383.395
- Create Date: 2020-01-11 22:43:52
- Modify Date: 2025-08-27 20:00:44
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A coumarin-based HIV-1 viral protein R (Vpr) inhibitor, inhibits Vpr-dependent viral infection of human macrophages.
| Name | NPD4456 |
|---|---|
| Synonyms |
Carbamic acid, N,N-dimethyl-, 3-(2,5-dimethoxyphenyl)-4-methyl-2-oxo-2H-1-benzopyran-7-yl ester
MFCD06765007 NPD4456 Dimethyl-carbamic acid 3-(2,5-dimethoxyphenyl)-4-methyl-2-oxo-2H-1-benzopyran-7-yl ester (9CI) 3-(2,5-Dimethoxyphenyl)-4-methyl-2-oxo-2H-chromen-7-yl dimethylcarbamate RIKEN Natural Product Derivative (NPD) 4456 |
| Description | A coumarin-based HIV-1 viral protein R (Vpr) inhibitor, inhibits Vpr-dependent viral infection of human macrophages. |
|---|---|
| References | References 1. Ong EB, et al. J Biol Chem. 2011 Apr 22;286(16):14049-56. View Related Products by Target HIV |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 568.8±50.0 °C at 760 mmHg |
| Molecular Formula | C21H21NO6 |
| Molecular Weight | 383.395 |
| Flash Point | 297.8±30.1 °C |
| Exact Mass | 383.136902 |
| LogP | 3.94 |
| Vapour Pressure | 0.0±1.6 mmHg at 25°C |
| Index of Refraction | 1.579 |
| Symbol |
GHS09 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H400 |
| Precautionary Statements | P273 |
| RIDADR | UN 3077 9 / PGIII |