m-PEG3-S-Acetyl

Modify Date: 2024-01-07 20:51:42

m-PEG3-S-Acetyl Structure
m-PEG3-S-Acetyl structure
Common Name m-PEG3-S-Acetyl
CAS Number 857284-78-7 Molecular Weight 222.30200
Density N/A Boiling Point N/A
Molecular Formula C9H18O4S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of m-PEG3-S-Acetyl


m-PEG3-S-Acetyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name tri(ethylene glycol) methyl ether thioacetate
Synonym More Synonyms

 m-PEG3-S-Acetyl Biological Activity

Description m-PEG3-S-Acetyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C9H18O4S
Molecular Weight 222.30200
Exact Mass 222.09300
PSA 70.06000
LogP 0.94570

 Precursor & DownStream

Precursor  0

DownStream  1

 Synonyms

(triethyleneglycol)thioacetate
methyltri(oxyethylene) thioacetate
M3OTA
triethylene glycol methyl ether thioacetate
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