m-PEG3-0-benzaldehyde

Modify Date: 2024-01-15 09:29:12

m-PEG3-0-benzaldehyde Structure
m-PEG3-0-benzaldehyde structure
Common Name m-PEG3-0-benzaldehyde
CAS Number 153364-63-7 Molecular Weight 268.306
Density 1.1±0.1 g/cm3 Boiling Point 383.8±32.0 °C at 760 mmHg
Molecular Formula C14H20O5 Melting Point N/A
MSDS N/A Flash Point 168.4±25.2 °C

 Use of m-PEG3-0-benzaldehyde


m-PEG3-0-benzaldehyde is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name 4-{2-[2-(2-Methoxyethoxy)ethoxy]ethoxy}benzaldehyde
Synonym More Synonyms

 m-PEG3-0-benzaldehyde Biological Activity

Description m-PEG3-0-benzaldehyde is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Density 1.1±0.1 g/cm3
Boiling Point 383.8±32.0 °C at 760 mmHg
Molecular Formula C14H20O5
Molecular Weight 268.306
Flash Point 168.4±25.2 °C
Exact Mass 268.131073
LogP 0.65
Vapour Pressure 0.0±0.9 mmHg at 25°C
Index of Refraction 1.510

 Synonyms

Benzaldehyde, 4-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]-
4-{2-[2-(2-Methoxyethoxy)ethoxy]ethoxy}benzaldehyde
MFCD22683279
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