2055041-00-2

2055041-00-2 structure

2055041-00-2 structure

Name: M-Peg3-sulfone-peg3-t-butyl ester
Chemical Name: m-PEG3-Sulfone-PEG3-Boc
CAS Number: 2055041-00-2
Molecular Formula: C₂₀H₄₀O₁₀S
Molecular Weight: 472.59
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2020-06-01 11:57:04
Modify Date: 2024-01-11 08:36:52
m-PEG3-Sulfone-PEG3-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	m-PEG3-Sulfone-PEG3-Boc
Synonyms	MFCD29918256

Description	m-PEG3-Sulfone-PEG3-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula	C₂₀H₄₀O₁₀S
Molecular Weight	472.59