PF-00337210

Modify Date: 2025-12-01 11:17:47

PF-00337210 Structure
PF-00337210 structure
Common Name PF-00337210
CAS Number 854514-88-8 Molecular Weight 461.51000
Density N/A Boiling Point N/A
Molecular Formula C26H27N3O5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of PF-00337210


A potent, selective, ATP-competitive and orally bioavailable inhibitor of VEGFR-2 with Ki of 0.7 and 8.8 nM for unactivated and fully phosphorylated VEGFR-2, respectively.

 Names

Name N,2-dimethyl-6{[7-(2-morpholin4-ylethoxy)quinolin-4-yl]oxy}-1-benzofuran-3-carboxamide
Synonym More Synonyms

 Chemical & Physical Properties

Molecular Formula C26H27N3O5
Molecular Weight 461.51000
Exact Mass 461.19500
PSA 86.06000
LogP 4.48110
InChIKey LGXVKMDGSIWEHL-UHFFFAOYSA-N
SMILES CNC(=O)c1c(C)oc2cc(Oc3ccnc4cc(OCCN5CCOCC5)ccc34)ccc12

 Synonyms

N,2-dimethyl-6-[7-(2-morpholinoethoxy)quinolin-4-yloxy]benzofuran-3-carboxamide
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