854514-88-8
854514-88-8 structure
- Name: PF-00337210
- Chemical Name: N,2-dimethyl-6{[7-(2-morpholin4-ylethoxy)quinolin-4-yl]oxy}-1-benzofuran-3-carboxamide
- CAS Number: 854514-88-8
- Molecular Formula: C26H27N3O5
- Molecular Weight: 461.51000
- Create Date: 2017-09-11 19:53:49
- Modify Date: 2024-07-19 10:32:22
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A potent, selective, ATP-competitive and orally bioavailable inhibitor of VEGFR-2 with Ki of 0.7 and 8.8 nM for unactivated and fully phosphorylated VEGFR-2, respectively.
| Name | N,2-dimethyl-6{[7-(2-morpholin4-ylethoxy)quinolin-4-yl]oxy}-1-benzofuran-3-carboxamide |
|---|---|
| Synonyms | N,2-dimethyl-6-[7-(2-morpholinoethoxy)quinolin-4-yloxy]benzofuran-3-carboxamide |
| Molecular Formula | C26H27N3O5 |
|---|---|
| Molecular Weight | 461.51000 |
| Exact Mass | 461.19500 |
| PSA | 86.06000 |
| LogP | 4.48110 |